Recent advancements in unmanned aerial systems and GPS technology, allowing for centimeter precision without ground-based surveys, have been groundbreaking for applications in the field of forestry. As this technology becomes integrated into forest management approaches, it is important to consider the implementation of proper safety and data collection strategies. The creation of such documentation is beneficial, because it allows for those aspiring to create a UAS program to learn from others’ experiences, without bearing the consequences of past blunders associated with the development of these practices. When establishing a UAS program, it is pertinent to deeply research the necessary equipment, create documentation that establishes operational norms, and develop standards for in-field operations. Regarding multispectral vs. RGB sensor payloads, the sensor selection should be based upon what type of information is desired from the imagery acquired. It is also important to consider the methods for obtaining the most precise geolocation linked to the aerial imagery collected by the sensor. While selecting the proper UAS platform and sensor are key to establishing a UAS operation, other logistical strategies, such as flight crew training and operational planning, are equally important. Following the acquisition of proper equipment, further preparations must be made in order to ensure safe and efficient operations. The creation of crew resource management and safety management system documentation is an integral part of any successful UAS program. Standard operating procedure documents for individual tasks and undertakings are also a necessity. Standardized practices for the scheduling, communication, and management of the UAS fleet must also be formulated. Once field operations are set in motion, the continuous improvement of the documentation and best practices is paramount.