Julien Orts is a physicist and biophysicist working at the interface of structural biology, NMR spectroscopy, and drug discovery. During his Ph.D. at the Max Planck Institute for Biophysical Chemistry and EMBL, he developed INPHARMA, an NMR method to experimentally validate how small molecules bind to proteins—now widely used in pharma and academia for complex targets like GPCRs. As a postdoc and junior group leader at ETH Zurich, he co-developed the exact NOE (eNOE) technique, which significantly improved the precision of NMR-based distance restraints and enabled atomic-resolution insights into protein structures and dynamics, even in large complexes. He also invented NMR2, the first fully automated method for determining protein–ligand complex structures from solution NMR data. Now Associate Professor and Scientific Director of the NMR Facility at the University of Vienna, Julien leads a lab focused on structure-based drug design, fragment screening, protein allostery, and the biophysical analysis of molecular interactions. His team also develops molecular probes for neurodegenerative diseases, combining computational and experimental strategies. Julien is a recipient of an ERC Consolidator Grant and Structural Funds for advanced research equipment. He is dedicated to pushing the boundaries of NMR in biomedical research and mentoring the next generation of scientists.