Recent construction trends on college campuses have demonstrated a shift to designing buildings with features focused on sustainability. However, few studies have investigated indoor air quality in institutions of higher education, particularly in sustainably designed buildings. The objective of this study was to evaluate the association of building and occupancy on indoor air quality within and between higher education buildings. We measured particulate matter, formaldehyde, carbon dioxide, and nitrogen oxides in LEED certified, retrofitted, and conventional building types on a college campus. Three size fractions of particulate matter were measured in each building. We conducted multi-zonal, 48-h measurements when the buildings were occupied and unoccupied. Outdoor particulate matter was significantly higher (PM2.5 = 4.76, PM4 = 17.1, and PM100 = 21.6 µg/m³) than in classrooms (PM2.5 = 1.7, PM4 = 4.2, and PM100 = 6.7 µg/m³) and common areas (PM2.5 = 1.3, PM4 = 4.2, and PM100 = 4.8 µg/m³; all p < 0.001). Additionally, concentrations of carbon dioxide and particulate matter were significantly higher (p < 0.05) during occupied sampling. The results suggest that occupancy status and building zone are major predictors of indoor air quality in campus buildings, which can, in turn, increase the concentration of contaminants, potentially impacting occupant health and performance. More research is warranted to reveal building features and human behaviors contributing to indoor exposures.

Background: Sugarcane workers in Central America experience a heavy burden of chronic kidney disease of unknown origin. We conducted a pilot study among worker proxies in Guatemala to characterize exposures to particulate matter, silica, heavy metals, and glyphosate, as well as to examine potential nephrotoxic exposures. Methods: Air, soil, and ash samples were collected and analyzed using scanning electron microscopy, X-ray diffraction, inductively coupled plasma mass spectrometry, and an enzyme-linked immunosorbent assay. Results: The average mass concentration for particulate matter (PM)_2.5 and PM₁₀₀ exposures were 360 µg/m³ (range: 32 to 1500 µg/m³) and 555 µg/m³ (range: 229 to 1170 µg/m³), respectively. The elemental composition of particles was largely silicon. The amount of crystalline silica was below 5 μg, yet the percentage of total silica was ~17% by weight. Putatively, the silica was in the amorphous form. Concentrations of aluminum and calcium ranged from 2–7 μg/m³. Glyphosate was not detectable in analyzed air samples but was detectable at concentrations ranging from 81–165 ppb in soil samples. Conclusion: Sugarcane workers are exposed to high concentrations of particulate matter. Future studies should investigate the potential role of silica, heavy metals, and agrochemicals in the etiology of chronic kidney disease in this population.