The histrionic growth of mobile subscribers, disruptive ecosystems such as IoT-based applications, and astounding channel capacity requirements to connect trillions of devices are massive challenges of the earlier mobile generations, 5G turned up the key solution. The prime objective of the 5G network is not only to maintain a 1000-fold capacity gain and 10 Giga Bits per second delivered to a single user, but it also assured quality-of-service, higher spectral efficiency, the ultra-reliable and improved battery lifetime of devices and massive machine-type communication (mMTC). The huge traffic load and high amount of resource consumption in 5G applications, augmented reality and virtual reality for magnificent virtual experience, and wireless body area networks will seriously affect the channel capacity of cellular cells and interrupt the admission and service of other users which makes compulsory new means of channel capacity and spectral efficiency enhancement techniques. In this research, we review several key emerging wireless technologies to increase channel capacity and spectral efficiency that will not only lead to improve network performance but also meets the ever-increasing user demands. We investigate various benefits and current research challenges of using these technologies. We analyze massive multi-input multi-output technology (mMIMO) an efficient technique and promising solution for the 5G and Beyond 5G (B5G) networks with several benefits and features. Moreover, this paper will be of vast help to the researchers who will involve advance investigation and also to the wireless network operator industry that is in the search for smooth development of state-of-the-art 5G and B5G networks.

Diabetic Retinopathy (DR) harm retinal blood vessels in the eye causing visual deficiency. The appearance and structure of blood vessels in retinal images play an essential part in the diagnoses of an eye sicknesses. We proposed a less computational unsupervised automated technique with promising results for detection of retinal vasculature by using morphological hessian based approach and region based Otsu thresholding. Contrast Limited Adaptive Histogram Equalization (CLAHE) and morphological filters have been used for enhancement and to remove low frequency noise or geometrical objects, respectively. The hessian matrix and eigenvalues approach used has been in a modified form at two different scales to extract wide and thin vessel enhanced images separately. Otsu thresholding has been further applied in a novel way to classify vessel and non-vessel pixels from both enhanced images. Finally, postprocessing steps has been used to eliminate the unwanted region/segment, non-vessel pixels, disease abnormalities and noise, to obtain a final segmented image. The proposed technique has been analyzed on the openly accessible DRIVE (Digital Retinal Images for Vessel Extraction) and STARE (STructured Analysis of the REtina) databases along with the ground truth data that has been precisely marked by the experts.

For the last two decades, physicians and clinical experts have used a single imaging modality to identify the normal and abnormal structure of the human body. However, most of the time, medical experts are unable to accurately analyze and examine the information from a single imaging modality due to the limited information. To overcome this problem, a multimodal approach is adopted to increase the qualitative and quantitative medical information which helps the doctors to easily diagnose diseases in their early stages. In the proposed method, a Multi-resolution Rigid Registration (MRR) technique is used for multimodal image registration while Discrete Wavelet Transform (DWT) along with Principal Component Averaging (PCAv) is utilized for image fusion. The proposed MRR method provides more accurate results as compared with Single Rigid Registration (SRR), while the proposed DWT-PCAv fusion process adds-on more constructive information with less computational time. The proposed method is tested on CT and MRI brain imaging modalities of the HARVARD dataset. The fusion results of the proposed method are compared with the existing fusion techniques. The quality assessment metrics such as Mutual Information (MI), Normalize Cross-correlation (NCC) and Feature Mutual Information (FMI) are computed for statistical comparison of the proposed method. The proposed methodology provides more accurate results, better image quality and valuable information for medical diagnoses.

Retinal vessel segmentation (RVS) is a significant source of useful information for monitoring, identification, initial medication, and surgical development of ophthalmic disorders. Most common disorders, i.e., stroke, diabetic retinopathy (DR), and cardiac diseases, often change the normal structure of the retinal vascular network. A lot of research has been committed to building an automatic RVS system. But, it is still an open issue. In this article, a framework is recommended for RVS with fast execution and competing outcomes. An initial binary image is obtained by the application of the MISODATA on the preprocessed image. For vessel structure enhancement, B‐COSFIRE filters are utilized along with thresholding to obtain another binary image. These two binary images are combined by logical AND‐type operation. Then, it is fused with the enhanced image of B‐COSFIRE filters followed by thresholding to obtain the vessel location map (VLM). The methodology is verified on four different datasets: DRIVE, STARE, HRF, and CHASE_DB1, which are publicly accessible for benchmarking and validation. The obtained results are compared with the existing competing methods.