Dr. Kewen Lei is a Professor at the Suzhou Institute of Nano-Tech and Nano-Bionics (SINANO), Chinese Academy of Sciences. He received his Bachelor’s (2014) and Master’s (2017) degrees from Fudan University, and earned his Ph.D. from the École Polytechnique Fédérale de Lausanne (EPFL) in 2022. Following his doctoral studies, he conducted postdoctoral research at the Massachusetts Institute of Technology (MIT). Dr. Lei’s research focuses on cancer immunotherapy, mechanical immunoengineering, and nucleic acid drug delivery systems. He is among the pioneering researchers to introduce the concept of “mechanical immunoengineering” into the field of biomedical science. His major scientific contributions include: • Discovery of tumor softness as a mechanical immune checkpoint regulating T-cell-mediated cytotoxicity; • Development of a T-cell force-responsive drug delivery system; • Development of an X-ray-opaque injectable thermogel for theranostic applications, including the prevention of postoperative adhesions and vascular embolism therapy. Dr. Lei has published over 15 peer-reviewed papers in leading journals such as Nature Biomedical Engineering, Accounts of Chemical Research, Materials Horizons, Acta Biomaterialia, and Chemical Communications. He is also a member of the Association for Cancer Immunotherapy (CIMT) and the European Academy of Tumor Immunology (EATI).