Translational health research is an interdisciplinary field aimed at bridging the gap between basic science studies, preventative studies, and clinical practice to improve health-related outcomes. Qualitative research methods provide a unique perspective on the emotional, social, cultural, and contextual factors that influence health and healthcare and thus are recognized as valuable tools for translational health research. This approach can be embedded within a mixed method design which complements the quantitative findings. This methodological paper aims to provide a comprehensive review of the fundamental concepts and methodologies used in qualitative research, emphasizing their utilization and significance in translational health research. Several approaches to qualitative research methodology are discussed in this review, including ethnography, phenomenology, grounded theory, case study, and action research. Theoretical frameworks such as the social-ecological model, intersectionality, and participatory action research are also examined to provide a structure for understanding and interpreting complex health issues. This methodological paper also reviews commonly used sampling techniques such as purposive, snowball, convenience, theoretical, and maximum variation sampling, along with data collection methods such as in-depth interviews, focus groups, observation, document analysis, and participatory methods. Moreover, data analysis techniques such as thematic analysis, grounded theory, content analysis, narrative analysis, and reflexive analysis, are discussed in the context of translational health. Overall, this review highlights the challenges and opportunities of using qualitative methods in current practice, while also discussing future directions and providing valuable guidance and insights to researchers interested in conducting qualitative research in translational health.

A mixed-methods approach combines qualitative and quantitative research methodologies to provide a comprehensive understanding of complex social phenomena in healthcare. This approach leverages the strengths of both methodologies to address research questions that cannot be fully answered by a single method. While quantitative data offer measurable patterns and generalizability, qualitative research provides critical insights into the human experiences, cultural contexts, and systemic factors that underlie these patterns, and such elements are often missed by purely statistical analyses. Notably, qualitative components can uncover why interventions succeed or fail in real-world settings, adding explanatory power to quantitative results. By integrating numerical data analysis with in-depth contextual insights, mixed-methods research enables researchers to explore, explain, and generalize findings in healthcare settings more holistically than either method could achieve alone.

Background: Migrant and refugee populations are disproportionately affected by the housing crises reportedly impacting high-income countries around the globe. However, the health implications of housing inequalities within these communities and contexts remain relatively understudied. This review aimed to synthesise the evidence on housing and health inequalities prevalent among migrant and refugee populations in high-income countries, and to identify the pathways linking housing inequalities and health outcomes. Methods: This systematic review employed the Joanna Briggs Institute (JBI) methodology for mixed-methods systematic reviews using a convergent integrated approach to synthesis and integration. Electronic database searches were conducted using Medline (OVID), Web of Science (ISI), Embase (OVID), PsycInfo (OVID), Scopus, and CINAHL (EBSCO), supplemented by grey literature searches on Google Scholar, MedNar, and WHOLIS. Eligible studies included quantitative, qualitative, and mixed methods designs focused on understanding how housing inequalities are associated with physical and mental health outcomes. Results: A total of 65 studies published between 1995 and 2024 were included in this review, comprising 38 quantitative and 27 qualitative studies. Substandard housing conditions, such as overcrowding and poor ventilation, were consistently associated with adverse physical and mental health outcomes, including respiratory illnesses and experiences of anxiety and depression. The type of housing tenure also impacted both physical and mental health, specifically living in inadequate rental housing as opposed to self-owned homes, was linked with poorer physical health and increased risk of mental health issues. Similarly, housing insecurity stemming from unstable housing situations and insecure tenancy, as well as neighbourhood conditions such as safety concerns and living in deprived neighbourhoods, led to the exacerbation of both physical and mental health issues. Furthermore, housing affordability challenges and decreased housing satisfaction were linked with poor mental health outcomes such as experiences of depression and psychological distress. Conclusions: This review highlights the critical role of housing as a social determinant of health and wellbeing for migrant and refugee populations in high-income countries, along with highlighting the potential pathways through which housing inequalities impact physical and mental health outcomes. Ensuring access to adequate, affordable, and secure housing, while also improving neighbourhood conditions, is essential for improving the health and wellbeing of migrant and refugee populations.

Interdisciplinary approaches are increasingly integral in doctoral and higher research education, addressing complex global challenges through collaborations across disciplines. This review investigates the benefits, challenges, and educational impact of interdisciplinary approaches in doctoral research. This scoping review follows the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) guidelines and uses an integrative narrative synthesis. The review was conducted using four major academic databases (ERIC, PubMed, Scopus, and Web of Science) with an exploratory search using keywords related to interdisciplinary approaches, doctoral studies, and academic collaborations. The review synthesized evidence from studies published in English, focusing on interdisciplinary research in doctoral education, with no restrictions on study design. Eligibility criteria were based on the SPIDER tool (Sample, Phenomenon of Interest, Design, Evaluation, Research Type). The search was completed on 25 September 2024. The initial search retrieved n = 954 articles, with n = 167 articles being reviewed for the integrative synthesis. The review included studies that examined interdisciplinary collaborations in doctoral research, highlighting the benefits such as skill versatility, career readiness, and research adaptability. The challenges discussed included academic culture differences, communication barriers, and institutional silos. The role of academic institutions and supervisors in supporting interdisciplinary research through fostering collaborative environments was emphasized. The review provides insights into how interdisciplinary approaches can enhance doctoral education, preparing graduates to tackle global challenges. It highlights the need for improved integration of interdisciplinary practices in doctoral research and outlines future directions for fostering interdisciplinary collaborations in higher education.

This study aimed to examine the trends in the prevalence of overweight and obesity and to determine the associated socioeconomic and household environmental factors among women in Nepal. Using nationally representative data from the 1996, 2001, 2006, 2011, and 2016 cross-sectional Nepal Demographic and Health Surveys (NDHSs) (n = 33,507), the prevalence of overweight–obesity (body mass index (BMI) ≥ 25 kg/m²) and obesity (BMI ≥ 30 kg/m²) among women aged 15–49 years were examined. From the latest NDHS 2016, non-pregnant women with recorded anthropometric measurements (n = 6165) were included in the final analyses. Multivariate logistic regression models were used to determine the socioeconomic and household environmental factors associated with BMI ≥ 25 and BMI ≥ 30. Between 1996 and 2016, the prevalence of overweight–obesity increased from 1.8% to 19.7%, while the prevalence of obesity increased from 0.2% to 4.1%. Age, marital status, wealth index, province of residence, type of cooking fuel, and household possessions—refrigerator and bicycle were significantly associated with having overweight–obesity and obesity. Similarly, educational status, religion, type of toilet facility, and household possessions—television and mobile phone were significantly associated with having overweight–obesity. Given the alarming increase in the prevalence of overweight and obesity among Nepalese women, there is an urgent need for interventions addressing these critical socioeconomic and household environmental factors.

Passive design integrates a wide range of climate-based strategies to increase occupant thermal comfort and minimise the need for mechanical systems for heating and cooling. The aim of this study was to improve the thermal comfort performance in a naturally ventilated residence through the identification and evaluation of the best set of passive design strategies. A two-storey residence located in Washington, United States with a temperate climate was selected as the case study residence. A reference simulation model was developed by replicating only the orientation and massing of the case study residence, while certain assumptions were made for other building characteristics. Thermal comfort performance analysis was conducted in the DesignBuilder software. A set of design strategies were introduced as interventions followed by simulation runs to efficiently track progress. From the reference simulation model to the final intervention model, a 50% reduction in the annual discomfort hours was anticipated in the five selected zones of the residence. Following the integration of four major interventions, the target discomfort hours were met in three zones—library, bedroom 1 and bedroom 2, with 53.03%, 60.42% and 58.94% reduction in discomfort hours, respectively. The two remaining zones—living and lounge also had a notable improvement with a reduction of 43.93% and 45.99%, respectively. The successful design strategies included—incorporation of triple glazed, low-emissivity and argon filled openings with wooden frames; integration of overhangs in south-facing windows, minor reduction of openings in the east and west façade, and addition of blinds for window shading; and use of an energy code standard construction for the building components and further addition of insulation in the building envelope. The most effective intervention was the customisation of the window operation schedule based on seasonal air temperature differences to optimise natural ventilation. This study demonstrated that occupant thermal comfort can be significantly improved throughout the year with the appropriate use of passive heating and cooling strategies, thereby reducing energy consumption and the environmental impact of buildings.