Khajamohiddin Syed received his PhD in Biochemistry from the Sri Krishnadeveraya University in 2006. He is a full professor of Biochemistry at the University of Zululand, South Africa. His research focus areas include bioinformatics, encompassing genome-wide studies, drug discovery, communicable and non-communicable diseases, structural biology, and evolution. Currently, his group focuses on the molecules listed below, along with some of the outstanding results: (i) Cytochrome P450 monooxygenases (CYPs/P450s) · Developed the P450ATLAST database (https://p450atlas.org/); · Discovered a novel P450-fusion protein in Oomycetes; · Proposed P450 family-specific signature sequence patterns; · Proposed mathematical formulas for P450 contingent analysis; · Proposed a hypothesis that is now widely accepted: P450s play a key role in organisms' adaptation vis-a-vis lifestyle impacts on P450 content in their genome · Unveiled how the P450s evolved in Archaea. (ii) Redox proteins (ferredoxins and flavodoxins) · Proposed a subtype classification for ferredoxins. (iii) Oncogenes and tumor suppressor genes. · Identified NF-κB proteins with multiple RHD-DBDs and RHD-DDs; · Proposed an evolutionary path for different types of NF-κB proteins.
University of Zululand
Empangeni, South Africa