Luana Carolina Santos Leite

Ms. Luana Carolina Santos Leite

Federal University of Mato Grosso do Sul, Campo Grande, Mato Grosso do Sul, Brazil
orcid

Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 January 2020 in BioMed Research International
Verified
Journal Article
Open access
PDF file
PTPaula F S Tschinkel
Paula F S Tschinkel
EMElaine S P Melo
Elaine S P Melo
HPHugo S Pereira
Hugo S Pereira
KSKassia R N Silva
Kassia R N Silva
DADaniela G Arakaki
Daniela G Arakaki
VNValter Aragão do Nascimento
Valter Aragão do Nascimento
The determination of Cd, Co, Cr, Cu, Fe, Na, Zn, and Pb by inductively coupled plasma‐optical emission spectrometry (ICP OES) was performed on dry matter and decoctions of the medicinal plants Cordia salicifolia, Chiococca alba (L.) Hitchc., and Echites peltata used as an appetite suppressant and diuretic in Brazil. The accuracy of the measurements was analyzed by the spike recovery test. Results showed that the concentration of these seven metals (Cd, Co, Cr, Cu, Fe, Na, and Zn) in dry plant samples is below the oral concentration of elemental impurities established by the United States Pharmacopoeia Convention (USP). However, there are no concentration limits for Fe, Na, and Zn established by the USP in drug substances and excipients. Levels higher than the recommended value by the USP were observed for Pb and the lowest for Cd, Co, Cr, and Cu, both in dried plant samples and their decoctions. In the decoctions prepared from these plants were found elements such as Cd, Co, Cr, Cu, Fe, Na, Zn, and Pb. In the decoction prepared from 40 g C. salicifolia leaves and 40 g C. alba wood, the content of Cd is above the oral daily exposure value set by the USP. Hazard index (HI) for decoctions prepared from these plants exceeded the threshold (1). Given the uncertainties associated with the estimates of toxicity values and exposure factors, futures researches should address the possible toxicity in humans. Uncontrolled selling and long‐term ingestion of medicinal plants can cause toxicity and interfere with the effect of drugs. Limited knowledge on the interaction potential of medicinal plants poses a challenge and public health problem in Brazil and other countries.

LLLuana Carolina Santos Leite
Luana Carolina Santos Leite
NLNayara Vieira de Lima
Nayara Vieira de Lima
EMElaine Melo
Elaine Melo
CCCarla Maiara Lopes Cardozo
Carla Maiara Lopes Cardozo
VNValter Aragão do Nascimento
Valter Aragão do Nascimento
The presence of heavy metals in the environment is increasing, which can be a danger to public health. Fish exposed to contaminated environments tend to have higher concentrations of some metals in their tissues. Monitoring these elements remains urgent as it is a matter of global concern. Canned sardines from the Brazilian market were analyzed for elements (Al, As, Ba, Cd, Co, Cr, Cu, Fe, Ni, Pb, Se, and Zn) of metals and metalloids, including some toxic, using inductively coupled plasma optical spectrometry (ICP OES) in two types of sardines (preserved in oil and tomato sauce) from five different brands. The results were compared to limit levels for consumption set by FAO/WHO. Moreover, we assessed the associated risk regarding the elemental intake of these elements through the samples, using the hazard quotient (HQ), hazard index (HI), and carcinogenic risk (CR). All samples had unfavorable HQ and HI, primarily due to arsenic content. In the same manner, CR for arsenic was above the proposed limit of 10−4, and cadmium and chromium, which were within the acceptable limit (10−6 to 10−4), require attention. These results show that chronic consumption of canned sardines sold in Brazil is unsafe, and quality surveillance is needed to ensure there is no risk to the population that ingests these products.

12 July 2024 in Biological Trace Element Research
Verified
Journal Article
Closed access
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RRRafaela Rosa
Rafaela Rosa
DADaniela Arakaki
Daniela Arakaki
EMElaine Melo
Elaine Melo
LLLuana Carolina Santos Leite
Luana Carolina Santos Leite
HPHugo Santos Pereira
Hugo Santos Pereira
VNValter Aragão do Nascimento
Valter Aragão do Nascimento

LLLuana Carolina Santos Leite
Luana Carolina Santos Leite
EMElaine Melo
Elaine Melo
DADaniela Arakaki
Daniela Arakaki
ESElisvania Freitas dos Santos
Elisvania Freitas dos Santos
VNValter Aragão do Nascimento
Valter Aragão do Nascimento
Data on the content of metals and metalloids in roasted meats with different types of wood and charcoal are still scarce in the literature. The concentrations of metals (Al, Cr, Cd, Cu, Fe, Mg, Mn, Mo, Ni, V, and Zn) and metalloid (As) were determined by inductively coupled plasma mass spectrometry (ICP-OES) after microwave digestion, and the estimated daily intake (EDI) for adults was assessed to determine the hazard quotient (HQ). The concentrations of Al, Cr, Cu, and Fe in raw meats were below the data obtained in other countries. The concentration of As (0.17 ± 0.42–0.23 ± 0.10 mg/kg), Mg (206.77 ± 3.99–291.95 ± 8.87 mg/kg), V (0.42 ± 0.14–6.66 ± 0.80 mg/kg), and Zn (6.66 ± 0.80–48.13 ± 0.56 mg/kg) in raw meats exceeded the values in the literature. The concentrations of Mg, As, Cr, Fe, V, and Zn are high when the meat is roasted using wood. All levels of Al, As, Cr, Cu, Fe, Mg, Mn, Mo, V, and Zn in raw meats are lower than those of meat roasted with coal and wood. The content of As in meat roasted with Chromed Copper Arsenate (CCA) wood (15.10 ± 0.27–26.25 ± 1.47 mg/kg) is higher than meat roasted with charcoal (0.46 ± 0.09–1.16 ± 0.50 mg/kg). EDI and HQ values revealed a minimal exposure of the adult population to those metals through roasted-meats consumption. However, EDI values of As in some roasted meats are above standard limits. Roast meats with wood showed higher levels of major and trace elements than meats roasted with coal. High exposures, in the long-term, may cause damage to health.

MOMarcelo Sampaio Ocampos
Marcelo Sampaio Ocampos
LLLuana Carolina Santos Leite
Luana Carolina Santos Leite
EMElaine Melo
Elaine Melo
RGRita De Cássia Avellaneda Guimarães
Rita De Cássia Avellaneda Guimarães
RORodrigo Juliano Oliveira
Rodrigo Juliano Oliveira
VNValter Aragão do Nascimento
Valter Aragão do Nascimento
People are constantly exposed to particulate matter and chemicals released during fires. However, there are still few studies on gas and particulate emissions related to exposure to burning firewood and charcoal during forest fires, making it difficult to understand the effects on the health of the population. The objective of this study was to quantify the metal(loid)s present in the smoke from wood and charcoal fires through the deposition of metals in beef topside and pork loin, considering the routes of skin exposure, inhalation, and ingestion, contributing to the understanding of metals in the increase of the risks of cancer and mortality associated with firefighting and children. The concentrations of metals [aluminum (Al), chromium (Cr), copper (Cu), iron (Fe), magnesium (Mg), manganese (Mn), molybdenum (Mo), vanadium (V), zinc (Zn)] and metalloids arsenic (As) were determined by inductively coupled plasma–mass spectrometry (ICP OES) after microwave digestion. Moreover, we assessed the associated risk regarding the elemental intake of these elements through the smoke, using the hazard quotient (HQ), hazard index (HI), Total Hazard Index (HIt), and carcinogenic risk (CR). All samples had results for HQ and HIt < 1, indicating a non-potential health risk. However, the carcinogenic risks posed by As and Cr via the three exposure pathways (except for inhalation exposure to children and adults, and by Cr via ingestion and inhalation for children and adults) exceeded the standard threshold. In conclusion, continuous exposure of firefighters or children to smoke from fires containing high concentrations of heavy metals such as As and Cr can be harmful to health. The study used animal tissues; thus, new methods must be developed to quantify the concentration of heavy metals deposited in human tissue when humans are exposed to smoke from fires.

18 September 2025 in Journal of Food Measurement and Characterization
Verified
Journal Article
Closed access
PDF file
CCCarla Maiara Lopes Cardozo
Carla Maiara Lopes Cardozo
EMElaine Melo
Elaine Melo
DADaniela Arakaki
Daniela Arakaki
LLLuana Carolina Santos Leite
Luana Carolina Santos Leite
MOMarcelo Oliveira
Marcelo Oliveira
VNValter Aragão do Nascimento
Valter Aragão do Nascimento