He has been engaged in research related to the collection, preservation, identification, evaluation, and innovative utilization of fruit tree resources. Main research directions include: pear resource collection, preservation, and utilization, identification and evaluation, as well as genetic relationship research; the creation of new germplasm with target traits, genetic analysis of important traits, and gene function identification research. From 2018 to 2019, He conducted collaborative research at Bioversity International, working on crop resource diversity conservation in the Lima office in Peru and the Rome headquarters in Italy. He has led or participated in 21 projects, published over 100 academic papers, including 38 first/corresponding author papers. As the first inventor, He has been granted 16 national invention patents, 2 international invention patents, 5 utility model patents, and 5 software copyrights. He has registered 15 new pear varieties, with 7 varieties receiving new plant variety protection.He has co-authored 2 books and contributed to 3 others, and have developed 3 agricultural industry standards. Currently, He has mentored 3 master's degree students.