Madalina Diac

Ms. Madalina Diac

University of Medicine and Pharmacy " Grigore T. Popa", iasi, Romania
orcid

Research Focus & Metrics

Academic Career Length

9Years (2018-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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17 September 2020 in Applied Sciences
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Journal Article
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Madalina DiacMadalina Diac
Madalina Diac
EKEarar Kamel
Earar Kamel
SDSimona Irina Damian
Simona Irina Damian
AKAnton Knieling
Anton Knieling
Tatiana IovTatiana Iov
Tatiana Iov
DIDiana Bulgaru Iliescu
Diana Bulgaru Iliescu
Craniofacial reconstruction often represents a final step in medico-legal identification and is dependent on facial tissue thickness measurements and feature shape estimation. This study’s aim is to create a reliable and readily reproductible method of predicting the maximum nose width (MNW) based on the maximum nasal aperture width (MAW) for a Romanian adult population. A sample of 55 computer tomography (CT) scans consisting of Romanian adult subjects was selected from the database of a neurosurgery hospital. The craniometrics measured consisted of a first measure of MAW and second one of the MNW using 3D systems Freeform Modelling Plus Software. Correlation analysis indicated a moderate link between the MAW and the MNW. Regression analysis showed that MAW and sex form a statistically significant regression pattern (R2 = 0.340, SEE (Standard Error of Estimate) = 3.801). The preliminary results obtained provide reliable predictions of MNW for facial reconstruction based on MAW measured on the skull.

15 December 2021 in Applied Sciences
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Journal Article
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Madalina DiacMadalina Diac
Madalina Diac
Tatiana IovTatiana Iov
Tatiana Iov
SDSimona Irina Damian
Simona Irina Damian
AKAnton Knieling
Anton Knieling
Nona GirlescuNona Girlescu
Nona Girlescu
DIDiana Bulgaru Iliescu
Diana Bulgaru Iliescu
The estimation of stature from bones plays an important role in identifying unknown bodies, body parts, or skeletal remains, as it is an important component of the biological profile in forensic identification. The objective of this study is to enhance the development of forensic anthropology in Romania by creating a new regression formula for stature estimation. This can be accomplished from the length of the tibia, taking into account sex and age, for the Romanian adult population. A total of 137 cases from a delimited territory of Romania were included in the study. The length of the tibia and the stature of the individuals were measured before autopsy. Statistical analysis was carried using (Statistical Package for the Social Sciences) SPSS 23. Tibia length showed a high correlation with stature for males, females, and the total sample. Four regression formulae were created for stature estimation of Romanian males, females, and unknown sex. The results of the analysis are impressive and have a good applicability in a forensic anthropological context. The data used in this paper provide reliable results with a large applicability in the future for estimating stature from the tibia length for the Romanian adult population.

2 September 2022 in Diagnostics
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AOAndrei Olteanu
Andrei Olteanu
GBGheorghe Bălan
Gheorghe Bălan
OTOana Timofte
Oana Timofte
CDCristina Gena Dascalu
Cristina Gena Dascalu
EGElena Gologan
Elena Gologan
Cristina Gabriela SchiopuCristina Gabriela Schiopu
Cristina Gabriela Schiopu
The assessment of fibrosis in chronic liver diseases using non-invasive methods is an important topic in hepatology. The aim of this study is to identify patients with non-alcoholic fatty liver disease (NAFLD) and advanced liver fibrosis by establishing correlations between biological/ultrasound markers and non-invasively measured liver stiffness. This study enrolled 116 patients with non-alcoholic fatty liver disease, which were evaluated clinically, biologically, and by ultrasound. Liver fibrosis was quantified by measuring liver stiffness by shear wave elastography (SWE). Multiple correlation analysis of predictors of liver fibrosis identified a number of clinical, biological, and ultrasound parameters (BMI, blood glucose, albumin, platelet count, portal vein diameter, bipolar spleen diameter) that are associated with advanced liver fibrosis in patients with non-alcoholic fatty liver disease. The correlations between the degree of liver fibrosis and the risk values of some serological and ultrasound markers obtained in our study could be useful in clinical practice for the identification of advanced fibrosis in patients with NAFLD.

8 December 2023 in Diagnostics
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Journal Article
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Madalina DiacMadalina Diac
Madalina Diac
GTGina Madalina Toma
Gina Madalina Toma
SDSimona Irina Damian
Simona Irina Damian
MFMarin Fotache
Marin Fotache
NRNicolai Romanov
Nicolai Romanov
DIDiana Bulgaru Iliescu
Diana Bulgaru Iliescu
Background: Identifying skeletal remains has been and will remain a challenge for forensic experts and forensic anthropologists, especially in disasters with multiple victims or skeletal remains in an advanced stage of decomposition. This study examined the performance of two machine learning (ML) algorithms in predicting the person’s sex based only on the morphometry of L1–L5 lumbar vertebrae collected recently from Romanian individuals. The purpose of the present study was to assess whether by using the machine learning (ML) techniques one can obtain a reliable prediction of sex in forensic identification based only on the parameters obtained from the metric analysis of the lumbar spine. Method: This paper built and tuned predictive models with two of the most popular techniques for classification, RF (random forest) and XGB (xgboost). Both series of models used cross-validation and a grid search to find the best combination of hyper-parameters. The best models were selected based on the ROC_AUC (area under curve) metric. Results: The L1–L5 lumbar vertebrae exhibit sexual dimorphism and can be used as predictors in sex prediction. Out of the eight significant predictors for sex, six were found to be particularly important for the RF model, while only three were determined to be important by the XGB model. Conclusions: Even if the data set was small (149 observations), both RF and XGB techniques reliably predicted a person’s sex based only on the L1–L5 measurements. This can prove valuable, especially when only skeletal remains are available. With minor adjustments, the presented ML setup can be transformed into an interactive web service, freely accessible to forensic anthropologists, in which, after entering the L1–L5 measurements of a body/cadaver, they can predict the person’s sex.

20 December 2019 in Revista Romaneasca pentru Educatie Multidimensionala
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Journal Article
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SDSimona Irina Damian
Simona Irina Damian
Madalina DiacMadalina Diac
Madalina Diac
Tatiana IovTatiana Iov
Tatiana Iov
IHIuliana Hunea
Iuliana Hunea
DIDiana Bulgaru Iliescu
Diana Bulgaru Iliescu
Particularities of Medical Education in the Field of Forensic Toxicology. Studying Dangerous Chemical Agents in Forensic Research

1 January 2020 in BRAIN. BROAD RESEARCH IN ARTIFICIAL INTELLIGENCE AND NEUROSCIENCE
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Madalina DiacMadalina Diac
Madalina Diac
IHIuliana Hunea
Iuliana Hunea
NGNona Girlescu
Nona Girlescu
AKAnton Knieling
Anton Knieling
SDSimona Irina Damian
Simona Irina Damian
DIDiana Bulgaru Iliescu
Diana Bulgaru Iliescu
The foramen magnum makes the transition between the cephalic extremity and the spine, which is an anatomical element of the skull. So, there are multiple situations when the skull is the only skeletal element available for anthropological analysis. In this respect, the foramen magnum can provide valuable information in terms of skeletal anthropological expertise. According to the literature, the foramen magnum provides, from a morphometric and morphological point of view, individual and population characteristics. The study aims to evaluate the morphometry of the foramen magnum for establish the sex of an unknown person, specific for Romanian adult population. The authors analyzed morphometrically the foramen magnum of 50 cranio-cerebral computer tomographic images. Measurements of the foramen magnum were taken anteroposterior diameter, transverse diameter, based on the two being calculated the anthropometric index and the area of the foramen magnum. Statistical analysis was carried out using SPSS 23. Discriminant function analysis was applied, and discriminant formulas were created for sex determination of Romanian adult population. The results of the analysis are impressive and have a good applicability in a forensic anthropological context. The data used in this paper provides reliable results with a large applicability in the future for estimating the sex from foramen magnum for Romanian adult population.