Ming Dao

Prof. Dr. Ming Dao

Department of Materials Science and Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts, USA
orcid

Research Focus & Metrics

Academic Career Length

34Years (1993-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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1 November 2001 in Acta Materialia
Verified
Journal Article
Closed access
Ming DaoMing Dao
Ming Dao
NCN. Chollacoop
N. Chollacoop
KVK.J. Van Vliet
K.J. Van Vliet
TVT.A. Venkatesh
T.A. Venkatesh
Suresh SeetharamanSuresh Seetharaman
Suresh Seetharaman

1 July 2007 in Acta Materialia
Verified
Journal Article
Closed access
Ming DaoMing Dao
Ming Dao
LLL Lu
L Lu
RAR Asaro
R Asaro
Jeff Th. M DeHossonJeff Th. M DeHosson
Jeff Th. M DeHosson
EME Ma
E Ma

18 September 2017 in Proceedings of the National Academy of Sciences
Verified
Journal Article
Closed access
PDF file
MWMengxi Wu
Mengxi Wu
YOYingshi Ouyang
Yingshi Ouyang
ZWZeyu Wang
Zeyu Wang
RZRui Zhang
Rui Zhang
PHPo-Hsun Huang
Po-Hsun Huang
Tony Jun HuangTony Jun Huang
Tony Jun Huang
Significance: We have developed a unique, integrated, on-chip technology that is capable of isolating exosomes or other types of extracellular vesicles, directly from undiluted whole-blood samples in an automated fashion. Automated exosome isolation enables biohazard containment, short processing time, reproducible results with little human intervention, and convenient integration with downstream exosome analysis units. Our method of integrating acoustics and microfluidics leads to the isolation of exosomes with high purity and yield. With its label-free, contact-free, and biocompatible nature, it offers the potential to preserve the structures, characteristics, and functions of isolated exosomes. This automated, point-of-care device can further help in advancing exosome-related biomedical research with potential applications in health monitoring, disease diagnostics, and therapeutics.

1 January 2005 in Acta Biomaterialia
Verified
Journal Article
Closed access
Suresh SeetharamanSuresh Seetharaman
Suresh Seetharaman
JSJ. Spatz
J. Spatz
JMJ.P. Mills
J.P. Mills
AMA. Micoulet
A. Micoulet
Ming DaoMing Dao
Ming Dao
TST. Seufferlein
T. Seufferlein

6 April 2015 in Proceedings of the National Academy of Sciences
Verified
Journal Article
Closed access
PDF file
PLPeng Li
Peng Li
ZMZhangming Mao
Zhangming Mao
ZPZhangli Peng
Zhangli Peng
LZLanlan Zhou
Lanlan Zhou
YCYuchao Chen
Yuchao Chen
Tony Jun HuangTony Jun Huang
Tony Jun Huang
Significance: The separation and analysis of circulating tumor cells (CTCs) provides physicians a minimally invasive way to monitor the response of cancer patients to various treatments. Among the existing cell-separation methods, acoustic-based approaches provide significant potential to preserve the phenotypic and genotypic characteristics of sorted cells, owing to their safe, label-free, and contactless nature. In this work, we report the development of an acoustic-based device that successfully demonstrates the isolation of rare CTCs from the clinical blood samples of cancer patients. Our work thus provides a unique means to obtain viable and undamaged CTCs, which can subsequently be cultured. The results presented here offer unique pathways for better cancer diagnosis, prognosis, therapy monitoring, and metastasis research.

1 November 2003 in Journal of the Mechanics and Physics of Solids
Verified
Journal Article
Closed access
Ming DaoMing Dao
Ming Dao
CLChwee Teck Lim
Chwee Teck Lim
Suresh SeetharamanSuresh Seetharaman
Suresh Seetharaman