Michael Le Grande

Dr. Michael Le Grande

The University of Melbourne, Melbourne, Victoria, Australia
orcid

Research Focus & Metrics

Academic Career Length

37Years (1990-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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29 January 2020 in Frontiers in Psychology
Verified
Journal Article
Open access
PDF file
BMBarbara Mary Murphy
Barbara Mary Murphy
MGMichael Le Grande
Michael Le Grande
MAMarlies Alvarenga
Marlies Alvarenga
MWMarian Worcester
Marian Worcester
AJAlun Jackson
Alun Jackson
Introduction: Patients who are anxious or depressed after an acute cardiac event are at increased risk of a subsequent event and premature death. It is therefore important to identify these patients early in order to initiate supportive or even preventive measures. In the present study, we report on the prevalence of anxiety and depression during the first 12 months after an acute cardiac event, and the patient characteristics predictive of increased anxiety and depression risk in early and late convalescence. Methods: We recruited a sample of 911 patients with acute myocardial infarction (AMI), acute coronary syndrome (ACS), and/or unstable angina (UA), and/or undergoing coronary artery bypass graft surgery (CABGS). Patients completed the Hospital Anxiety and Depression Scale (HADS) close to the time of their event, and again during early (2–4 months post-event) and late (6–12 months post-event) convalescence. Using HADS-A and HADS-D cut-offs of 8+, prevalence rates for anxiety, depression, and comorbid anxiety and depression were determined for each timepoint. Chi-square tests and odds ratios were used to identify baseline patient characteristics associated with increased anxiety and depression risk over 12 months. Results: Anxiety rates were 43, 28, and 27% at the time of the event, early, and late convalescence. Depression rates were 22, 17, and 15%, respectively. Factors consistently associated with increased anxiety and depression risk were history of depression, financial strain, poor self-rated health, low socioeconomic status, younger age (<55 years), and smoking. Obesity, diabetes, and social isolation (living alone or being unpartnered) were identified as important albeit less significant risk factors. Neither sex nor event type were predictive of anxiety or depression. Conclusion: This large patient sample provided the opportunity to identify rates of anxiety and depression during the 12 months after a cardiac event and key patient characteristics for increased risk. These risk factors are easily identifiable at the time of the event, and could be used to guide the targeting of support programs for patients at risk.

1 August 2017 in Social Science & Medicine
Verified
Journal Article
Closed access
MGMichael Le Grande
Michael Le Grande
CSChantal Ski
Chantal Ski
David R ThompsonDavid R Thompson
David R Thompson
Paul ScuffhamPaul Scuffham
Paul Scuffham
SKS. Kularatna
S. Kularatna
ABA. Brown
A. Brown

1 August 2008 in European Journal of Preventive Cardiology
Verified
Journal Article
Closed access
BMBarbara Mary Murphy
Barbara Mary Murphy
PEPeter C. Elliott
Peter C. Elliott
RHRosemary O. Higgins
Rosemary O. Higgins
MGMichael Le Grande
Michael Le Grande
MWMarian U.C. Worcester
Marian U.C. Worcester
JTJames Tatoulis
James Tatoulis
Background To target interventions, patients at risk for poor outcomes after a cardiac event need to be identified. We investigated trajectories of anxiety and ...

1 April 2008 in European Journal of Preventive Cardiology
Verified
Journal Article
Closed access
BMBarbara Mary Murphy
Barbara Mary Murphy
PEPeter C. Elliott
Peter C. Elliott
MGMichael Le Grande
Michael Le Grande
RHRosemary O. Higgins
Rosemary O. Higgins
CEChristine S. Ernest
Christine S. Ernest
MWMarian U.C. Worcester
Marian U.C. Worcester
Background Earlier studies show that medical factors and disease severity predict early readmission to hospital after coronary artery bypass graft surgery (CABG...

1 February 2008 in British Journal of Health Psychology
Verified
Journal Article
Closed access
PDF file
BMBarbara Mary Murphy
Barbara Mary Murphy
PEPeter C. Elliott
Peter C. Elliott
MWMarian U. C. Worcester
Marian U. C. Worcester
RHRosemary O. Higgins
Rosemary O. Higgins
MGMichael Le Grande
Michael Le Grande
AGAlan J. Goble
Alan J. Goble

16 June 2008 in Medical Journal of Australia
Verified
Journal Article
Closed access
PDF file
RHRosemary O Higgins
Rosemary O Higgins
BMBarbara Mary Murphy
Barbara Mary Murphy
AGAlan J Goble
Alan J Goble
MGMichael Le Grande
Michael Le Grande
PEPeter C Elliott
Peter C Elliott
MWMarian U C Worcester
Marian U C Worcester
Objective: To investigate rates and predictors of cardiac rehabilitation (CR) attendance after coronary artery bypass graft surgery (CABGS) at Royal Melbourne Hospital (RMH), Victoria, where current ...