Applications of machine learning algorithms (MLAs) to modeling the adsorption efficiencies of different heavy metals have been limited by the adsorbate–adsorbent pair and the selection of specific MLAs. In the current study, adsorption efficiencies of fourteen heavy metal–adsorbent (HM-AD) pairs were modeled with a variety of ML models such as support vector regression with polynomial and radial basis function kernels, random forest (RF), stochastic gradient boosting, and bayesian additive regression tree (BART). The wet experiment-based actual measurements were supplemented with synthetic data samples. The first batch of dry experiments was performed to model the removal efficiency of an HM with a specific AD. The ML modeling was then implemented on the whole dataset to develop a generalized model. A ten-fold cross-validation method was used for the model selection, while the comparative performance of the MLAs was evaluated with statistical metrics comprising Spearman’s rank correlation coefficient, coefficient of determination (R²), mean absolute error, and root-mean-squared-error. The regression tree methods, BART, and RF demonstrated the most robust and optimum performance with 0.96 ⫹ R² ⫹ 0.99. The current study provides a generalized methodology to implement ML in modeling the efficiency of not only a specific adsorption process but also a group of comparable processes involving multiple HM-AD pairs.

The recent Coronavirus Disease 2019 (COVID-19) pandemic has put a tremendous burden on global health systems. Medical practitioners are under great pressure for reliable screening of suspected cases employing adjunct diagnostic tools to standard point-of-care testing methodology. Chest X-rays (CXRs) are appearing as a prospective diagnostic tool with easy-to-acquire, low-cost and less cross-contamination risk features. Artificial intelligence (AI)-attributed CXR evaluation has shown great potential for distinguishing COVID-19-induced pneumonia from other associated clinical instances. However, one of the associated challenges with diagnostic imaging-based modeling is incorrect feature attribution, which leads the model to learn misguiding disease patterns, causing wrong predictions. Here, we demonstrate an effective deep learning-based methodology to mitigate the problem, thereby allowing the classification algorithm to learn from relevant features. The proposed deep-learning framework consists of an ensemble of convolutional neural network (CNN) models focusing on both global and local pathological features from CXR lung images, while the latter is extracted using a multi-instance learning scheme and a local attention mechanism. An inspection of a series of backbone CNN models using global and local features, and an ensemble of both features, trained from high-quality CXR images of 1311 patients, further augmented for achieving the symmetry in class distribution, to localize lung pathological features followed by the classification of COVID-19 and other related pneumonia, shows that a DenseNet161 architecture outperforms all other models, as evaluated on an independent test set of 159 patients with confirmed cases. Specifically, an ensemble of DenseNet161 models with global and local attention-based features achieve an average balanced accuracy of 91.2%, average precision of 92.4%, and F1-score of 91.9% in a multi-label classification framework comprising COVID-19, pneumonia, and control classes. The DenseNet161 ensembles were also found to be statistically significant from all other models in a comprehensive statistical analysis. The current study demonstrated that the proposed deep learning-based algorithm can accurately identify the COVID-19-related pneumonia in CXR images, along with differentiating non-COVID-19-associated pneumonia with high specificity, by effectively alleviating the incorrect feature attribution problem, and exploiting an enhanced feature descriptor.

The traditional procedure of predicting the settling velocity of a spherical particle is inconvenient as it involves iterations, complex correlations, and an unpredictable degree of uncertainty. The limitations can be addressed efficiently with artificial intelligence-based machine-learning algorithms (MLAs). The limited number of isolated studies conducted to date were constricted to specific fluid rheology, a particular MLA, and insufficient data. In the current study, the generalized application of ML was comprehensively investigated for Newtonian and three varieties of non-Newtonian fluids such as Power-law, Bingham, and Herschel Bulkley. A diverse set of nine MLAs were trained and tested using a large dataset of 967 samples. The ranges of generalized particle Reynolds number (Re_G) and drag coefficient (C_D) for the dataset were 10⁻³ < Re_G (-) < 10⁴ and 10⁻¹ < C_D (-) < 10⁵, respectively. The performances of the models were statistically evaluated using an evaluation metric of the coefficient-of-determination (R²), root-mean-square-error (RMSE), mean-squared-error (MSE), and mean-absolute-error (MAE). The support vector regression with polynomial kernel demonstrated the optimum performance with R² = 0.92, RMSE = 0.066, MSE = 0.0044, and MAE = 0.044. Its generalization capability was validated using the ten-fold-cross-validation technique, leave-one-feature-out experiment, and leave-one-data-set-out validation. The outcome of the current investigation was a generalized approach to modeling the settling velocity.

Gas–liquid flow is a significant phenomenon in various engineering applications, such as in nuclear reactors, power plants, chemical industries, and petroleum industries. The prediction of the flow patterns is of great importance for designing and analyzing the operations of two-phase pipeline systems. The traditional numerical and empirical methods that have been used for the prediction are known to result in a high inaccuracy for scale-up processes. That is why various artificial intelligence-based (AI-based) methodologies are being applied, at present, to predict the gas–liquid flow regimes. We focused in the current study on a thorough comparative analysis of machine learning (ML) and deep learning (DL) in predicting the flow regimes with the application of a diverse set of ML and DL frameworks to a database comprising 11,837 data points, which were collected from thirteen independent experiments. During the pre-processing, the big data analysis was performed to analyze the correlations among the parameters and extract important features. The comparative analysis of the AI-based models’ performances was conducted using precision, recall, F1-score, accuracy, Cohen’s kappa, and receiver operating characteristics curves. The extreme gradient boosting method was identified as the optimum model for predicting the two-phase flow regimes in inclined or horizontal pipelines.

Pancreatic cancer (PC) has one of the lowest survival rates among all major types of cancer. Consequently, it is one of the leading causes of mortality worldwide. Serum biomarkers historically correlate well with the early prognosis of post-surgical complications of PC. However, attempts to identify an effective biomarker panel for the successful prognosis of PC were almost non-existent in the current literature. The current study investigated the roles of various serum biomarkers including carbohydrate antigen 19-9 (CA19-9), chemokine (C-X-C motif) ligand 8 (CXCL-8), procalcitonin (PCT), and other relevant clinical data for identifying PC progression, classified into sepsis, recurrence, and other post-surgical complications, among PC patients. The most relevant biochemical and clinical markers for PC prognosis were identified using a random-forest-powered feature elimination method. Using this informative biomarker panel, the selected machine-learning (ML) classification models demonstrated highly accurate results for classifying PC patients into three complication groups on independent test data. The superiority of the combined biomarker panel (Max AUC-ROC = 100%) was further established over using CA19-9 features exclusively (Max AUC-ROC = 75%) for the task of classifying PC progression. This novel study demonstrates the effectiveness of the combined biomarker panel in successfully diagnosing PC progression and other relevant complications among Egyptian PC survivors.