Na'il Saleh

Prof. Dr. Na'il Saleh

United Arab Emirates University
orcid

Research Focus & Metrics

Academic Career Length

30Years (1997-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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7 July 2008 in Angewandte Chemie International Edition
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Journal Article
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Na'il SalehNa'il Saleh
Na'il Saleh
AKApurba Lal Koner
Apurba Lal Koner
WNWerner M. Nau
Werner M. Nau

23 January 2014 in Journal of the American Chemical Society
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Journal Article
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NNNaba K. Nath
Naba K. Nath
LPLjupčo Pejov
Ljupčo Pejov
SNShane M. Nichols
Shane M. Nichols
CHChunhua Hu
Chunhua Hu
Na'il SalehNa'il Saleh
Na'il Saleh
PNPanče Naumov
Panče Naumov

7 July 2022 in Nature Communications
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Journal Article
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GDGobinda Das
Gobinda Das
BGBikash Garai
Bikash Garai
TPThirumurugan Prakasam
Thirumurugan Prakasam
FBFarah Benyettou
Farah Benyettou
SVSabu Varghese
Sabu Varghese
ATAli Trabolsi
Ali Trabolsi
Ionic covalent organic frameworks (iCOFs) are new examples of porous materials and have shown great potential for various applications. When functionalized with suitable emission sites, guest uptake via the ionic moieties of iCOFs can cause a significant change in luminescence, making them excellent candidates for chemosensors. In here, we present a luminescence sensor in the form of an ionic covalent organic framework (TGH+•PD) composed of guanidinium and phenanthroline moieties for the detection of ammonia and primary aliphatic amines. TGH+•PD exhibits strong emission enhancement in the presence of selective primary amines due to the suppression of intramolecular charge transfer (ICT) with an ultra-low detection limit of 1.2 × 10‒7M for ammonia. The presence of ionic moieties makes TGH+•PD highly dispersible in water, while deprotonation of the guanidinium moiety by amines restricts its ICT process and signals their presence by enhanced fluorescence emission. The presence of ordered pore walls introduces size selectivity among analyte molecules, and the iCOF has been successfully used to monitor meat products that release biogenic amine vapors upon decomposition due to improper storage.

1 February 2011 in Canadian Journal of Chemistry
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Journal Article
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AKApurba Lal Koner
Apurba Lal Koner
IGIndrajit GhoshI. Ghosh
Indrajit GhoshI. Ghosh
Na'il SalehNa'il Saleh
Na'il Saleh
WNWerner M. Nau
Werner M. Nau
UV–vis and NMR spectroscopic techniques were employed to demonstrate the ability of the synthetic macrocyclic host cucurbit[7]uril (CB7) to solubilize and stabilize widely used fungicides and anthelmintic drugs of the benzimidazole family in water, namely, albendazole (ABZ), carbendazim (CBZ), thiabendazole (TBZ), fuberidazole (FBZ), and the parent benzimidazole (BZ). CB7 binds the protonated forms of these guests very strongly (e.g., K = 2.6 × 107 L/mol for ABZ) but their neutral forms significantly more weakly (e.g., K = 6.5 × 104 L/mol for ABZ), which reflects a complexation-induced increase of their pKa values by 2.6 units for ABZ, 2.5 units for CBZ, 4.0 units for TBZ, 3.8 units for FBZ, and 3.5 units for BZ. The absolute drug solubilities increased upon complexation from 0.003 to 0.300 mmol/L for ABZ, from 0.160 to 1.12 mmol/L for CBZ, from 0.110 to 1.11 mmol/L for TBZ, and from 0.25 to 0.75 mmol/L for FBZ (for BZ, the solubility enhancement was found to be insignificant). Complexation by CB7 further improves the photostability of the drugs and alters their photophysical properties.


5 February 2015 in RSC Advances
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Journal Article
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MRM. A. Rauf
M. A. Rauf
SHSoleiman Hisaindee
Soleiman Hisaindee
Na'il SalehNa'il Saleh
Na'il Saleh
Azo dyes account for 60–70% of all dyes known to date. Understanding the factors that affect the direction of keto–enol tautomerism in azo dyes through spectral measurements is crucial to their potential applications. This review encompasses the most important spectroscopic studies of different azo dyes categorized by their structures within the last few years (2010–2014). It is concluded that the stability of the keto and enol forms largely arises from the ability to establish intra-molecular and inter-molecular hydrogen bonding, respectively. There are many factors that affect the keto or enol form, for example, polar solvent, high temperature, neutral pH and electron withdrawing substituents favor the keto form through intramolecular hydrogen bonding, whereas, nonpolar solvent, low temperature, high pH and electron donating groups favor the enol form through intermolecular hydrogen bonding. Encapsulation inside nanocaged microheterogenous systems creates a rigid environment that stabilizes the enol form mostly, while in the solid state, most of the tautomeric equilibrium lies in favor of the keto form. Understanding of keto–enol tautomerism in azo dyes helps to probe solvation dynamics, to tune the pKa values in chemical sensing, and to explain proton transfer in the excited state.