Efficiency mapping has an important place in examining the maximum efficiency distribution as well as the energy consumption of designed electric motors at maximum torque and speed. Performing analysis at all operating points with FEM analysis in the motor design process requires high processing costs and time. In this article, a machine learning-based multivariate polynomial regression estimation model was developed to overcome these costly processes from FEM analysis. With the proposed method, the operating points of the motors in different conditions during the design process can be predicted in advance with high accuracy. In the study, two different models are developed for efficiency map and core loss estimation of interior permanent magnet synchronous motor design. The developed models use few parameters and predict with high accuracy. Estimation models shorten the design process and offer a less complex model. Obtained results are validated by comparison with FEM analysis.