Paolo Malune

Dr. Paolo Malune

Department of Life and Environmental Sciences, University of Cagliari, Italy, Cagliari, Sardegna, Italy
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Biography

Specialized in molecular virology with a strong background in antiviral drug discovery. Graduated with honors in Medical Biotechnologies at the University of Padua, with a thesis project focused on the genomic characterization of SARS-CoV-2 circulating in Central Sardinia. This training was followed by a Ph.D. in Life, Environmental and Drug Sciences at the University of Cagliari, centered on the identification and biochemical evaluation of inhibitors targeting SARS-CoV-2 RdRp. Research experience spans clinical genetics, microbiology, and drug discovery, including work on cell-based antiviral assays, enzymatic assays, recombinant protein production and biophysics methods to study protein-protein and protein-ligand interactions. Additional activities include international research periods and contributions as a teaching laboratory assistant in molecular microbiology. The scientific output comprises multiple peer-reviewed publications on SARS-CoV-2 polymerase and protease inhibition, as well as participation in national and international conferences with poster and oral presentations. Current work as a postdoctoral researcher focuses on the biochemical and biophysical characterization of viral polymerases and on the development of assays to identify novel antiviral compounds.

Affiliations

University of Cagliari, Italy

Cagliari, Sardegna, Italy

Department of Life and Environmental Sciences

Honors and Awards

No honors or awards have been shared yet.

Experience

Post Doctoral Researcher

University of Cagliari, Cagliari, Italy

01 Apr 2025 - present