Most oncological cases can be detected by imaging techniques, but diagnosis is based on pathological assessment of tissue samples. In recent years, the pathology field has evolved to a digital era where tissue samples are digitised and evaluated on screen. As a result, digital pathology opened up many research opportunities, allowing the development of more advanced image processing techniques, as well as artificial intelligence (AI) methodologies. Nevertheless, despite colorectal cancer (CRC) being the second deadliest cancer type worldwide, with increasing incidence rates, the application of AI for CRC diagnosis, particularly on whole-slide images (WSI), is still a young field. In this review, we analyse some relevant works published on this particular task and highlight the limitations that hinder the application of these works in clinical practice. We also empirically investigate the feasibility of using weakly annotated datasets to support the development of computer-aided diagnosis systems for CRC from WSI. Our study underscores the need for large datasets in this field and the use of an appropriate learning methodology to gain the most benefit from partially annotated datasets. The CRC WSI dataset used in this study, containing 1,133 colorectal biopsy and polypectomy samples, is available upon reasonable request.

Considering the profound transformation affecting pathology practice, we aimed to develop a scalable artificial intelligence (AI) system to diagnose colorectal cancer from whole-slide images (WSI). For this, we propose a deep learning (DL) system that learns from weak labels, a sampling strategy that reduces the number of training samples by a factor of six without compromising performance, an approach to leverage a small subset of fully annotated samples, and a prototype with explainable predictions, active learning features and parallelisation. Noting some problems in the literature, this study is conducted with one of the largest WSI colorectal samples dataset with approximately 10,500 WSIs. Of these samples, 900 are testing samples. Furthermore, the robustness of the proposed method is assessed with two additional external datasets (TCGA and PAIP) and a dataset of samples collected directly from the proposed prototype. Our proposed method predicts, for the patch-based tiles, a class based on the severity of the dysplasia and uses that information to classify the whole slide. It is trained with an interpretable mixed-supervision scheme to leverage the domain knowledge introduced by pathologists through spatial annotations. The mixed-supervision scheme allowed for an intelligent sampling strategy effectively evaluated in several different scenarios without compromising the performance. On the internal dataset, the method shows an accuracy of 93.44% and a sensitivity between positive (low-grade and high-grade dysplasia) and non-neoplastic samples of 0.996. On the external test samples varied with TCGA being the most challenging dataset with an overall accuracy of 84.91% and a sensitivity of 0.996.

This paper presents a summary of the Masked Face Recognition Competitions (MFR) held within the 2021 International Joint Conference on Biometrics (IJCB 2021). The competition attracted a total of 10 participating teams with valid submissions. The affiliations of these teams are diverse and associated with academia and industry in nine different countries. These teams successfully submitted 18 valid solutions. The competition is designed to motivate solutions aiming at enhancing the face recognition accuracy of masked faces. Moreover, the competition considered the deployability of the proposed solutions by taking the compactness of the face recognition models into account. A private dataset representing a collaborative, multisession, real masked, capture scenario is used to evaluate the submitted solutions. In comparison to one of the topperforming academic face recognition solutions, 10 out of the 18 submitted solutions did score higher masked face verification accuracy.

Colorectal cancer (CRC) diagnosis is based on samples obtained from biopsies, assessed in pathology laboratories. Due to population growth and ageing, as well as better screening programs, the CRC incidence rate has been increasing, leading to a higher workload for pathologists. In this sense, the application of AI for automatic CRC diagnosis, particularly on whole-slide images (WSI), is of utmost relevance, in order to assist professionals in case triage and case review. In this work, we propose an interpretable semi-supervised approach to detect lesions in colorectal biopsies with high sensitivity, based on multiple-instance learning and feature aggregation methods. The model was developed on an extended version of the recent, publicly available CRC dataset (the CRC+ dataset with 4433 WSI), using 3424 slides for training and 1009 slides for evaluation. The proposed method attained 90.19% classification ACC, 98.8% sensitivity, 85.7% specificity, and a quadratic weighted kappa of 0.888 at slide-based evaluation. Its generalisation capabilities are also studied on two publicly available external datasets.

Over the years, the evolution of face recognition (FR) algorithms has been steep and accelerated by a myriad of factors. Motivated by the unexpected elements found in real-world scenarios, researchers have investigated and developed a number of methods for occluded face recognition (OFR). However, due to the SarS-Cov2 pandemic, masked face recognition (MFR) research branched from OFR and became a hot and urgent research challenge. Due to time and data constraints, these models followed different and novel approaches to handle lower face occlusions, i.e., face masks. Hence, this study aims to evaluate the different approaches followed for both MFR and OFR, find linked details about the two conceptually similar research directions and understand future directions for both topics. For this analysis, several occluded and face recognition algorithms from the literature are studied. First, they are evaluated in the task that they were trained on, but also on the other. These methods were picked accordingly to the novelty of their approach, proven state-of-the-art results, and publicly available source code. We present quantitative results on 4 occluded and 5 masked FR datasets, and a qualitative analysis of several MFR and OFR models on the Occ-LFW dataset. The analysis presented, sustain the interoperable deployability of MFR methods on OFR datasets, when the occlusions are of a reasonable size. Thus, solutions proposed for MFR can be effectively deployed for general OFR.

SARS-CoV-2 has presented direct and indirect challenges to the scientific community. One of the most prominent indirect challenges advents from the mandatory use of face masks in a large number of countries. Face recognition methods struggle to perform identity verification with similar accuracy on masked and unmasked individuals. It has been shown that the performance of these methods drops considerably in the presence of face masks, especially if the reference image is unmasked. We propose FocusFace, a multi-task architecture that uses contrastive learning to be able to accurately perform masked face recognition. The proposed architecture is designed to be trained from scratch or to work on top of state-of-the-art face recognition methods without sacrificing the capabilities of a existing models in conventional face recognition tasks. We also explore different approaches to design the contrastive learning module. Results are presented in terms of masked-masked (M-M) and unmasked-masked (U-M) face verification performance. For both settings, the results are on par with published methods, but for M-M specifically, the proposed method was able to outperform all the solutions that it was compared to. We further show that when using our method on top of already existing methods the training computational costs decrease significantly while retaining similar performances. The implementation and the trained models are available at GitHub.