Daniele Perrina

Dr. Daniele Perrina

General, Emergency, and Trauma Surgery, Ausl Romagna, Cesena, Italy
orcid

Research Focus & Metrics

Academic Career Length

7Years (2020-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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18 October 2024 in World Journal of Emergency Surgery
Verified
Journal Article
Open access
PDF file
GSGiacomo Sermonesi
Giacomo Sermonesi
RBRiccardo Bertelli
Riccardo Bertelli
FPFredric M. Pieracci
Fredric M. Pieracci
ZBZsolt J. Balogh
Zsolt J. Balogh
RCRaul Coimbra
Raul Coimbra
FCFausto Catena
Fausto Catena
Rib fractures are one of the most common traumatic injuries and may result in significant morbidity and mortality. Despite growing evidence, technological advances and increasing acceptance, surgical stabilization of rib fractures (SSRF) remains not uniformly considered in trauma centers. Indications, contraindications, appropriate timing, surgical approaches and utilized implants are part of an ongoing debate. The present position paper, which is endorsed by the World Society of Emergency Surgery (WSES), and supported by the Chest Wall Injury Society, aims to provide a review of the literature investigating the use of SSRF in rib fracture management to develop graded position statements, providing an updated guide and reference for SSRF. This position paper was developed according to the WSES methodology. A steering committee performed the literature review and drafted the position paper. An international panel of experts then critically revised the manuscript and discussed it in detail, to develop a consensus on the position statements. A total of 287 studies (systematic reviews, randomized clinical trial, prospective and retrospective comparative studies, case series, original articles) have been selected from an initial pool of 9928 studies. Thirty-nine graded position statements were put forward to address eight crucial aspects of SSRF: surgical indications, contraindications, optimal timing of surgery, preoperative imaging evaluation, rib fracture sites for surgical fixation, management of concurrent thoracic injuries, surgical approach, stabilization methods and material selection. This consensus document addresses the key focus questions on surgical treatment of rib fractures. The expert recommendations clarify current evidences on SSRF indications, timing, operative planning, approaches and techniques, with the aim to guide clinicians in optimizing the management of rib fractures, to improve patient outcomes and direct future research.

1 July 2020 in The American Journal of Surgery
Verified
Journal Article
Closed access
ACand Federico Coccolini
and Federico Coccolini
DPDaniele Perrina
Daniele Perrina
MCMarco Ceresoli
Marco Ceresoli
YKYoram Kluger
Yoram Kluger
AKAndrew Kirkpatrick
Andrew Kirkpatrick
FCFausto Catena
Fausto Catena

20 September 2025 in Antibiotics
Verified
Journal Article
Open access
PDF file
MLMartina Leandri
Martina Leandri
CVCarlo Vallicelli
Carlo Vallicelli
GSGiorgia Santandrea
Giorgia Santandrea
DPDaniele Perrina
Daniele Perrina
FBFrancesca Bravi
Francesca Bravi
Fausto CatenaFausto Catena
Fausto Catena
Acute appendicitis remains one of the most common surgical emergencies, with a lifetime incidence of approximately 7–8% in the USA and Europe. Despite the widespread adoption of the laparoscopic approach and advances made in perioperative care, post-operative infections—particularly intra-abdominal abscesses—continue to pose a substantial clinical challenge, with an overall probability that ranges from 5 to 15%. Nowadays, it is essential not only to improve patient outcomes by reducing these complications but also to promote responsible antibiotic use. This review provides an in-depth examination of post-appendectomy infections in adults, synthesizing research from the past decade. It explores the various risks involved, including those related to the patient, the disease itself, and the surgical techniques employed. There is particular emphasis on the impact of surgical approach, closure methods, timing of surgery, and intraoperative decisions such as drain placement, peritoneal lavage, and routine bacterial cultures. Part of the discussion is about emerging data regarding the use of antiseptic solutions and specimen retrieval techniques. Additionally, the review examines current approaches to managing postoperative intra-abdominal abscesses. It assesses when antibiotics are necessary, evaluates image-guided percutaneous drainage, and considers laparoscopic re-intervention as a possible solution. While recent studies offer valuable insights, the heterogeneity of available evidence highlights the pressing need for high-quality, standardized research. Ultimately, a deeper understanding of infection pathways and preventative strategies is vital—not only for reducing morbidity and hospital readmissions, but also for safeguarding the long-term efficacy of antibiotics and delivering safer, more effective surgical care.

8 April 2024 in Journal of Gastrointestinal Surgery
Verified
Journal Article
Closed access
MSMauro Stefano
Mauro Stefano
DPDaniele Perrina
Daniele Perrina
CVCarlo Vallicelli
Carlo Vallicelli
LALuca Ansaloni
Luca Ansaloni
PFPaola Fugazzola
Paola Fugazzola
FCFausto Catena
Fausto Catena

11 February 2025 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
CVCarlo Vallicelli
Carlo Vallicelli
SBSilvia Jasmine Barbara
Silvia Jasmine Barbara
EFElisa Fabbri
Elisa Fabbri
DPDaniele Perrina
Daniele Perrina
GGGriggio Griggio
Griggio Griggio
Fausto CatenaFausto Catena
Fausto Catena
Rectal cancer is a significant global health concern, particularly amongst the elderly population, with rectal cancer accounting for approximately one-third of cancer cases in this population. Older adults often present with advanced disease stages and unique clinical manifestations, such as tumors closer to the anal verge and with greater size. Diagnosis typically involves a series of screening and imaging strategies, culminating in accurate staging through pelvic MRI, endoscopic ultrasound, and CT scan. Management of rectal cancer in older adults emphasizes individualized treatment plans that consider both the cancer stage and the patient’s overall health status, including frailty and comorbidities. A multidisciplinary approach, including a mandatory geriatric assessment, is essential for optimizing outcomes, in order to improve survival and quality of life for elderly patients with rectal cancer.

Verified
Journal Article
Open access
PDF file
APAlessandro Palladino
Alessandro Palladino
CVCarlo Vallicelli
Carlo Vallicelli
DPDaniele Perrina
Daniele Perrina
GCGirolamo Convertini
Girolamo Convertini
ACand Federico Coccolini
and Federico Coccolini
Fausto CatenaFausto Catena
Fausto Catena
Critically ill patients treated in the intensive care unit (ICU) can present with many abdominal conditions that need a prompt diagnosis and timely treatment because of their general frailty. Clinical evaluation and diagnostic tools like ultrasound or CT scans are not reliable or feasible in these patients. Bedside laparoscopy (BSL) is a minimally invasive procedure that allows surgeons to assess the abdominal cavity directly in the ICU, thus avoiding unnecessary exploratory laparotomy or incidents related to intra-hospital transfer. We conducted a review of the literature to summarize the state-of-the-art of BSL. The Medline, Cochrane Central Register of Controlled Trials (CENTRAL), and Scopus databases were utilized to identify all relevant publications. Indications, contraindications, technical aspects, and outcomes are discussed. The procedure is safe, feasible, and effective. When other diagnostic tools fail to diagnose or exclude an intra-abdominal condition in ICU patients, BSL should be preferred over exploratory laparotomy.