Paolo Muiesan graduated in Medicine at the University of Brescia (Italy). He continued his education as acting intern in University of California Davis, as resident in General Surgery and then further specialized in Vascular Surgery at the University of Milan. He trained in adult and pediatric liver transplantation and hepatobiliary surgery at King′s College Hospital in London. To complete his training in HPB Surgery and Liver Transplantation he visited the University of Nebraska Medical Center and the University of Western Ontario in 1996 and Kyoto University Transplant Centre in 1998. He became Consultant Surgeon in HPB Surgery and Transplantation at King’s College Hospital in 1998 and moved to Birmingham Queen Elizabeth and Children’s Hospitals ten years later. He visited the Asan Medical Centre in Seoul in 2008 and 2009 in preparation to start the Living Donor Liver Transplant program in Birmingham and attended several courses on laparoscopic liver surgery. He became Professor in HPB Surgery and Transplantation at University of Birmingham in 2015. Professor Muiesan lead the living donor, auxiliary, domino and DCD liver transplantation programs in Birmingham. Other clinical and research interests include normothermic regional perfusion and machine perfusion as novel means of organ preservation for transplantation. His interests also include liver resections for cholangiocarcinoma, ALPPS and ex-situ, ante-situ liver resections.