Internet of Things (IoT) is a new paradigm that has changed the traditional way of living into a high tech life style. Smart city, smart homes, pollution control, energy saving, smart transportation, smart industries are such transformations due to IoT. A lot of crucial research studies and investigations have been done in order to enhance the technology through IoT. However, there are still a lot of challenges and issues that need to be addressed to achieve the full potential of IoT. These challenges and issues must be considered from various aspects of IoT such as applications, challenges, enabling technologies, social and environmental impacts etc. The main goal of this review article is to provide a detailed discussion from both technological and social perspective. The article discusses different challenges and key issues of IoT, architecture and important application domains. Also, the article bring into light the existing literature and illustrated their contribution in different aspects of IoT. Moreover, the importance of big data and its analysis with respect to IoT has been discussed. This article would help the readers and researcher to understand the IoT and its applicability to the real world.

Pre-trained language models (PLMs) have been the de facto paradigm for most natural language processing tasks. This also benefits the biomedical domain: researchers from informatics, medicine, and computer science communities propose various PLMs trained on biomedical datasets, e.g., biomedical text, electronic health records, protein, and DNA sequences for various biomedical tasks. However, the cross-discipline characteristics of biomedical PLMs hinder their spreading among communities; some existing works are isolated from each other without comprehensive comparison and discussions. It is nontrivial to make a survey that not only systematically reviews recent advances in biomedical PLMs and their applications but also standardizes terminology and benchmarks. This article summarizes the recent progress of pre-trained language models in the biomedical domain and their applications in downstream biomedical tasks. Particularly, we discuss the motivations of PLMs in the biomedical domain and introduce the key concepts of pre-trained language models. We then propose a taxonomy of existing biomedical PLMs that categorizes them from various perspectives systematically. Plus, their applications in biomedical downstream tasks are exhaustively discussed, respectively. Last, we illustrate various limitations and future trends, which aims to provide inspiration for the future research.

Technology and the rapid growth in the area of brain imaging technologies have forever made for a pivotal role in analyzing and focusing the new views of the brain anatomy and functions. The mechanism of image processing has a widespread usage in the area of medical science for improving the early detection and treatment phases. Deep Neural Network (DNN), till date have demonstrated a wonderful performance in classification and segmentation task. Carrying this idea into consideration, in this paper a technique for image compression using a Deep Wavelet Autoencoder (DWA), which blends the basic feature reduction property of autoencoder along with image decomposition property of wavelet transform is proposed. The combination of both has a tremendous effect on sinking the size of the feature set for enduring further classification task by using DNN. A brain image dataset was taken and the proposed DWA-DNN image classifier was considered. The performance criterion for the DWA-DNN classifier was compared with other existing classifiers like Autoencoder-DNN or DNN, and it was noted that the proposed method outshines the existing methods.