Valko-Rokytovská M, et al. J Vet Sci. 2019 Oct;21:e23. https://doi.org/10.4142/jvs.2020.21.e23

Remission of diabetes mellitus in dogs is a very rare condition. In our case, the clinical signs of diabetes mellitus in the nine‐ year‐old Yorkshire terrier bitch disappeared three months after a therapeutic ovariohysterectomy. The diagnosis of diestrous diabetes mellitus, requiring insulin supplementation, was confirmed on the basis of anamnesis, symptomatology, clinical examination and specific laboratory tests. The chosen therapy and a change in diet led to the stabilization of the patient and its preparation for surgery. Repeated follow‐ups, consisting of control blood samplings for glucose and progesterone levels and urinanalysis, has ensured control of insulin therapy and proper insulin dosing. Three weeks after ovariohysterectomy, normoglycaemia, confirmed by control trials, resulted in gradual discontinuation of insulin administration. The stable health status of the patient two months after the performance of therapeutic ovariohysterectomy confirmed the remission of the disease without the need for further insulin supplementation and regular monitoring.