Blockchain transactions are decentralized, secure, and transparent, and they have altered industries. However, the emergence of quantum computing presents a severe security risk to the traditional encryption algorithms used in blockchain. Post-quantum signatures are required to preserve integrity and reliability. Furthermore, combining the InterPlanetary File System (IPFS) with blockchain provides a long-term strategy for data storage and sharing. This study investigates the integration of post-quantum signatures with the IPFS in a blockchain system, which can considerably enhance blockchain system efficiency. We increase security and efficiency by recording hash values of signatures and public keys within the blockchain and storing their actual content using the IPFS. The study compares NIST-recommended post-quantum signatures with the ECDSA in a Bitcoin exchange scheme to show how effective the system is in countering quantum threats while maintaining optimal performance. This research makes an important addition to the long-term viability and dependability of blockchain technology in the face of the growing landscape of quantum computing breakthroughs.