Hsin-Fang Tu

Dr. Hsin-Fang Tu

orcid

Biography

I’m an Associate Research Scientist at Yale, driven by a fascination with how our immune system recognizes and fights cancer. My work centers on understanding how CD8⁺ T cells become activated—or sometimes fail to—within tumors and their draining lymph nodes. I combine single-cell RNA-seq, TCR-seq, and spatial-omics to uncover the cellular programs that shape these immune responses. Much of my research focuses on head and neck cancers and HPV-associated lesions, exploring how the tumor microenvironment and lymph nodes coordinate or suppress anti-tumor immunity. I also previously worked at Johns Hopkins University, where I engineered cytokine-based molecules to modulate immune cell function and fine-tune the tumor microenvironment to boost cancer vaccine efficacy. With a Ph.D. in molecular biology and years of experience in tumor immunology, I’m passionate about translating mechanistic insights into new therapeutic strategies that re-engage the immune system to treat cancer more effectively.

Affiliations

No affiliation has been shared yet.

Honors and Awards

No honors or awards have been shared yet.

Experience

No experience has been shared yet.