Samuel Joseph Apple

Dr. Samuel Joseph Apple

New York City Health and Hospitals Corporation, New York, USA

Research Focus & Metrics

Academic Career Length

5Years (2022-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
11 March 2022 in Diagnostics
Verified
Journal Article
Open access
PDF file
YWYu Chiang Wang
Yu Chiang Wang
XXXiaobo Xu
Xiaobo Xu
AHADRIJA HAJRA
ADRIJA HAJRA
SASamuel Joseph Apple
Samuel Joseph Apple
AKAmrin Kharawala
Amrin Kharawala
RFRobert T. Faillace
Robert T. Faillace
Atrial fibrillation (AF) is a common arrhythmia affecting 8–10% of the population older than 80 years old. The importance of early diagnosis of atrial fibrillation has been broadly recognized since arrhythmias significantly increase the risk of stroke, heart failure and tachycardia-induced cardiomyopathy with reduced cardiac function. However, the prevalence of atrial fibrillation is often underestimated due to the high frequency of clinically silent atrial fibrillation as well as paroxysmal atrial fibrillation, both of which are hard to catch by routine physical examination or 12-lead electrocardiogram (ECG). The development of wearable devices has provided a reliable way for healthcare providers to uncover undiagnosed atrial fibrillation in the population, especially those most at risk. Furthermore, with the advancement of artificial intelligence and machine learning, the technology is now able to utilize the database in assisting detection of arrhythmias from the data collected by the devices. In this review study, we compare the different wearable devices available on the market and review the current advancement in artificial intelligence in diagnosing atrial fibrillation. We believe that with the aid of the progressive development of technologies, the diagnosis of atrial fibrillation shall be made more effectively and accurately in the near future.

4 July 2024 in Heart Rhythm
Verified
Journal Article
Closed access
SASamuel Joseph Apple
Samuel Joseph Apple
MPMatthew Parker
Matthew Parker
DFDavid Flomenbaum
David Flomenbaum
SRShalom M. Rosenbaum
Shalom M. Rosenbaum
JBJacob Borck
Jacob Borck
KFKevin J. Ferrick
Kevin J. Ferrick

30 March 2023 in Journal of Clinical Medicine
Verified
Journal Article
Open access
PDF file
ZCZhu CUI
Zhu CUI
FCFrancesco Castagna
Francesco Castagna
WHWaqas Hanif
Waqas Hanif
SASamuel Joseph Apple
Samuel Joseph Apple
LZLili Zhang
Lili Zhang
LSLeandro Slipczuk
Leandro Slipczuk
Patients with multiple myeloma (MM) are at a high risk for developing cardiovascular complications. Global longitudinal strain (GLS) can detect early functional impairment before structural abnormalities develop. It remains unknown if reduced GLS is associated with reduced survival in patients with MM. We conducted a retrospective cohort analysis of patients diagnosed with MM between 1 January 2000 and 31 December 2017 at our institution. Patients with a 2D transthoracic echocardiogram completed within 1 year of MM diagnosis, left ventricular ejection fraction (LVEF) greater than 40%, and no history of myocardial infarction prior to MM diagnosis were included. GLS was measured using an artificial-intelligence-powered software (EchoGo Core), with reduced GLS defined as an absolute value of 9.6, LVEF/GLS > 4.1, higher LV mass index, and low-voltage ECG. A Total of 126 (52.1%) deaths occurred during follow-up. Overall survival was lower among patients with reduced GLS (adjusted HR: 1.81, CI: 1.07–3.05).

11 July 2023 in The American Journal of Cardiology
Verified
Journal Article
Closed access
SASamuel Joseph Apple
Samuel Joseph Apple
DFDavid Flomenbaum
David Flomenbaum
MPMatthew Parker
Matthew Parker
SCSanya Chhikara
Sanya Chhikara
ASAaron Stolarov
Aaron Stolarov
KFKevin J. Ferrick
Kevin J. Ferrick

7 November 2024 in Journal of Cardiovascular Electrophysiology
Verified
Journal Article
Closed access
VSVikyath Satish
Vikyath Satish
MMMaisha Maliha
Maisha Maliha
KCKuan‐Yu Chi
Kuan‐Yu Chi
AKAmrin Kharawala
Amrin Kharawala
JSJiyoung Seo
Jiyoung Seo
KFKevin Ferrick
Kevin Ferrick

9 September 2025 in Heart Rhythm
Verified
Journal Article
Closed access
SASamuel Joseph Apple
Samuel Joseph Apple
SRShalom Rosenbaum
Shalom Rosenbaum
MGMichael Grushko
Michael Grushko
LBLuigi Di Biase
Luigi Di Biase
KFKevin J. Ferrick
Kevin J. Ferrick
JGJay N. Gross
Jay N. Gross