Sardar Sindhu

Dr. Sardar Sindhu

Dasman Diabetes Institute, Kuwait City, Al ‘Āşimah, Kuwait
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Biography

Dr. Sardar Sindhu received his Ph.D. in Immunology and Virology from the University of Montreal (2005) and completed postgraduate training in Experimental Medicine at McGill University (2007). Previously, he received his D.V.M. degree in 1985 and a master’s in Microbiology and Immunology in 1989. He also taught graduate/post-graduate courses in Advanced Immunology, General and Systemic Bacteriology/Virology, Mycology, and Microbial Physiology. His postdoctoral research at CHUM, Canada (2005-2007), and the Montreal Clinical Research Institute (IRCM, Canada) (2008-2011) involved studies on HIV-1/AIDS-driven immunopathogenesis, identifying the NK and γδ-T cell impairment as well as CD4+T cytocidal responses of Vpr-primed immune effectors. At present, his main research interests include metabolic inflammation, insulin resistance, and the role of various co-players, such as oxidative stress, TLRs as nutrient sensors, other TLR-downstream co-players (IRF5/7, FOXO1), and inflammatory cytokines/chemokines and adipokines. Dr. Sardar leads research focusing on the pathophysiological role of oxidative and ER stresses to understand the intimate links between metabolic inflammation, insulin resistance, and adipose tissue reprogramming. He also co-leads pathomolecular studies investigating the mechanisms and pathways of immunometabolic derangements, following high-fat diets fed to various KO mouse models lacking expression of critical inflammatory genes including Tnfa, Il6, Tlr2, and Tlr4.

Affiliations

Dasman Diabetes Institute

Kuwait City, Al ‘Āşimah, Kuwait

Honors and Awards

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Experience

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