Sascha W. Hoffmann graduated 2009 from the Johannes Gutenberg-University of Mainz, Germany, where he subsequently did his training in Sport Science with the special topic of prevention and rehabilitation and cardiology as well as orthopedics. After is diploma, he started is PhD in the working group of Prof. Dr. Dr. Perikles Simon. In 2012, he moved to University of Bayreuth, Germany, and joined the team of Sports Medicine to work with Professor Walter Schmidt. In 2014, he successfully finished his PhD with the title “The Children Health Study of Mainz: New perspectives for overweight prevention and general health promotion - An epidemiological approach”. In 2018 he became the Head of Department Sport Science VI – Theory and Practice of Sports at the BaySpo – Bayreuth Center of Sport Science at the University of Bayreuth. In 2025 he completed his habilitation (venia legendi in sport science). In the winter term 26/27 he also was the Head of Department Exercise Physiology and Metabolism at the BaySpo. His research activities focus mainly on the interaction between sedentary behavior and physical activity and its physiological responses on the human body. He has published several peer-reviewed manuscripts and book chapters in highly ranked journals. Since 2023, he is a review editor of the Editorial Board of Frontiers in Public Health and Nutrition. He awarded the German BKK Health Innovation Award 2014 “Lifestyle and common diseases” in 2015.