Sasimanas Unajak has expertise in aquatic animal diseases. His research interests include fish vaccine design based on conventional and reverse vaccinology, such as 1) a combined streptococcal vaccine, 2) a chimeric multiepitope vaccine design platform, 3) subunit DNA and protein vaccine preparation and production, and 4) oral vaccines for fish. In addition, Sasimanas is an expert in aptamer screening for disease and chemical detection.