Purpose: This study aimed to investigate the associations of the traits of autism spectrum disorder (ASD) and attention deficit hyperactivity disorder (ADHD) with depression and empathy among medical students. Patients and Methods: A cross-sectional survey was conducted with 202 fifth-year students at a Japanese medical school for 10 months during their clinical clerkship. The survey included sociodemographic questions and validated tools to measure depressive symptoms (Hospital Anxiety and Depression Scale [HADS]), medical students’ empathy for patients (Jefferson Scale of Empathy-Student version [JSE]), ADHD traits (ADHD Self-Report Scale Screener [ASRS Screener]), and ASD traits (Autism-Spectrum Quotient Japanese version-21 [AQ-J-21]). Results: A total of 151 students (response rate: 74.7%) participated in the survey. Of these, 41 (27.2%) reported a total score of ≥ 20 on the HADS and were categorized as depressed. Depressed students reported significantly lower and higher rates of having a part-time job and a history of enrolment in other faculties, respectively, than non-depressed students. According to the cutoff criteria of the ASRS Screener and AQ-J-21, 31 (20.5%) and 42 (27.8%) students reported ADHD and ASD traits, respectively. Multivariate regression analysis, controlling for age and sex, reported that higher age, ASRS Screener scores, and AQ-J-21 scores were significant predictors of higher HADS total scores. Additionally, higher AQ-J-21 scores significantly predicted lower JSE scores. Conclusion: The degree of ADHD and ASD traits was significantly associated with depression. Moreover, the degree of ASD traits was significantly associated with lower empathy for their patients. It is important to consider that about 20– 30% of medical students have these neurodevelopmental traits and to develop intervention strategies for improving depression and empathy.

This study aimed to develop and validate a Japanese version of the Tinnitus Acceptance Questionnaire (TAQ), an instrument that measures the process of intentional acceptance of adverse experiences associated with tinnitus. A total of 125 patients with chronic tinnitus from multiple institutions participated in this study. Participants completed the Japanese versions of the TAQ, Tinnitus Handicap Inventory, Valuing Questionnaire, Acceptance and Action Questionnaire-II, and Hospital Anxiety and Depression Scale. A second TAQ was administered 1–2 weeks later. Because the model fitted poorly in confirmatory factor analysis, exploratory factor analysis was conducted, which yielded a two-factor structure that was divided into forward and reversed item groups. Hypotheses regarding criterion and construct validity were clearly supported. A high Cronbach’s α coefficient value was obtained for the TAQ total score (0.88). The interclass correlation coefficient for test–retest reliability was within the acceptable range (0.95). The results of the exploratory factor analysis were considered to be due to artifacts caused by the characteristics of the Japanese language. The present study confirmed the validity and reliability of the Japanese version of the TAQ in measuring tinnitus-specific receptivity.

Background: Tinnitus retraining therapy (TRT) promotes habituation in chronic tinnitus but is less effective in patients under psychological distress. Acceptance and commitment therapy (ACT) offers an alternative by enhancing psychological flexibility rather than targeting symptom reduction. Case Presentation: Five patients with chronic tinnitus unresponsive to TRT completed the ACT program. Among them, four completed the 6‐month follow‐up and are presented in detail. While Case 1 was previously reported, this analysis includes all four to explore ACT's broader application. The intervention targeted ACT's six core processes. Outcomes were measured using the Tinnitus Handicap Inventory (THI), Cognitive Fusion Questionnaire‐7 (CFQ‐7), Valuing Questionnaire (VQ), and Hospital Anxiety and Depression Scale (HADS). After 6 months, three patients showed a clinically meaningful THI reduction. Those without hearing loss improved more in CFQ‐7 and HADS. VQ scores showed minimal change. Conclusion: ACT may help patients with TRT‐resistant tinnitus, particularly those without hearing loss.