My research primarily focuses on exploring the intricate mechanisms underlying cancer progression, with a particular emphasis on the interplay between metabolic reprogramming and tumor malignancy. Through multi-omics analyses and functional experiments, I have investigated the role of lncRNAs in gastric cancer metastasis, identifying that the EGR1-mediated lncRNA TENM3-AS1 promotes metastasis by reprogramming fatty acid metabolism via the hnRNPK/FASN axis. Additionally, my work on triple-negative breast cancer (TNBC) has dissected the heterogeneous tumor immune microenvironment, revealing the prognostic significance of immune cell subsets like IL32high Tregs and constructing a Malignant Cell Index based on key genes (including UQCRFS1) to predict patient outcomes and immunotherapy responses. I have also studied fatty acid metabolism-related signatures in breast cancer, establishing their association with immunosuppressive microenvironments and therapy resistance. My academic interests lie in unraveling the complex crosstalk between the tumor immune microenvironment and metabolic rewiring in cancer metastasis. I aim to identify novel biomarkers and therapeutic targets that bridge these processes, contributing to the development of more effective strategies for cancer diagnosis and treatment.