Thales Lima Silva

Ms. Thales Lima Silva

Genética e Melhoramento Animal, Unesp, Jaboticabal, Brazil
+2
orcid
PhD in Genetics and Animal Breeding

Research Focus & Metrics

Academic Career Length

11Years (2016-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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29 September 2022 in Animals
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Journal Article
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IFIvan Carvalho Filho
Ivan Carvalho Filho
DSDelvan Alves Silva
Delvan Alves Silva
CTCaio de Souza Teixeira
Caio de Souza Teixeira
Thales Lima SilvaThales Lima Silva
Thales Lima Silva
Lucio Flavio Macedo MotaLucio Flavio Macedo Mota
Lucio Flavio Macedo Mota
RCRoberto Carvalheiro
Roberto Carvalheiro
The assessment of the presence of genotype by environment interaction (GxE) in beef cattle is very important in tropical countries with diverse climatic conditions and production systems. The present study aimed to assess the presence of GxE by using different reaction norm models for eleven traits related to growth, reproduction, and visual score in Nellore cattle. We studied five reaction norm models (RNM), fitting a linear model considering homoscedastic residual variance (RNM_homo), and four models considering heteroskedasticity, being linear (RNM_hete), quadratic (RNM_quad), linear spline (RNM_l-l), and quadratic spline (RNM_q-q). There was the presence of GxE for age at first calving (AFC), scrotal circumference (SC), weaning to yearling weight gain (WYG), and yearling weight (YW). The best models were RNM_l-l for YW and RNM_q-q for AFC, SC, and WYG. The heritability estimates for RNM_l-l ranged from 0.07 to 0.20, 0.42 to 0.61, 0.24 to 0.42, and 0.47 to 0.63 for AFC, SC, WYG, and YW, respectively. The heteroskedasticity in reaction norm models improves the assessment of the presence of GxE for YW, WYG, AFC, and SC. Additionally, the trajectories of reaction norms for these traits seem to be affected by a non-linear component, and selecting robust animals for these traits is an alternative to increase production and reduce environmental sensitivity.

1 December 2019 in Livestock Science
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Journal Article
Closed access
Thales Lima SilvaThales Lima Silva
Thales Lima Silva
PCPaulo Luiz Souza Carneiro
Paulo Luiz Souza Carneiro
DADiego Pagung Ambrosini
Diego Pagung Ambrosini
RLRaysildo Barbosa Lôbo
Raysildo Barbosa Lôbo
RFRaimundo Martins Filho
Raimundo Martins Filho
CMCarlos Henrique Mendes Malhado
Carlos Henrique Mendes Malhado

16 August 2023 in Frontiers in Genetics
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Journal Article
Open access
Thales Lima SilvaThales Lima Silva
Thales Lima Silva
CGCedric Gondro
Cedric Gondro
PFPablo Augusto de Souza Fonseca
Pablo Augusto de Souza Fonseca
DSDelvan Alves da Silva
Delvan Alves da Silva
GVGiovana Vargas
Giovana Vargas
RCRoberto Carvalheiro
Roberto Carvalheiro
Beef cattle affected by feet and legs malformations (FLM) cannot perform their productive and reproductive functions satisfactorily, resulting in significant economic losses. Accelerated weight gain in young animals due to increased fat deposition can lead to ligaments, tendon and joint strain and promote gene expression patterns that lead to changes in the normal architecture of the feet and legs. The possible correlated response in the FLM due to yearling weight (YW) selection suggest that this second trait could be used as an indirect selection criterion. Therefore, FLM breeding values and the genetic correlation between FLM and yearling weight (YW) were estimated for 295,031 Nellore animals by fitting a linear-threshold model in a Bayesian approach. A genome-wide association study was performed to identify genomic windows and positional candidate genes associated with FLM. The effects of single nucleotide polymorphisms (SNPs) on FLM phenotypes (affected or unaffected) were estimated using the weighted single-step genomic BLUP method, based on genotypes of 12,537 animals for 461,057 SNPs. Twelve non-overlapping windows of 20 adjacent SNPs explaining more than 1% of the additive genetic variance were selected for candidate gene annotation. Functional and gene prioritization analysis of candidate genes identified six genes (ATG7, EXT1, ITGA1, PPARD, SCUBE3, and SHOX) that may play a role in FLM expression due to their known role in skeletal muscle development, aberrant bone growth, lipid metabolism, intramuscular fat deposition and skeletogenesis. Identifying genes linked to foot and leg malformations enables selective breeding for healthier herds by reducing the occurrence of these conditions. Genetic markers can be used to develop tests that identify carriers of these mutations, assisting breeders in making informed breeding decisions to minimize the incidence of malformations in future generations, resulting in greater productivity and animal welfare.

2 November 2022 in Journal of Animal Breeding and Genetics
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Journal Article
Closed access
Thales Lima SilvaThales Lima Silva
Thales Lima Silva
CGCedric Gondro
Cedric Gondro
PFPablo Augusto de Souza Fonseca
Pablo Augusto de Souza Fonseca
DSDelvan Alves Silva
Delvan Alves Silva
GVGiovana Vargas
Giovana Vargas
RCRoberto Carvalheiro
Roberto Carvalheiro

20 January 2016 in Revista IPecege
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Thales Lima SilvaThales Lima Silva
Thales Lima Silva
AFAna Flávia Gouveia de Faria
Ana Flávia Gouveia de Faria
O objetivo deste trabalho foi demonstrar a utilização da estatística como ferramenta para minimizar o risco em operações de hedge de boi gordo, tendo como base a série histórica de preços na cidade de Itapetinga no estado da Bahia. Os preços no mercado futuro foram obtidos junto ao Centro de Estudos Avançados em Economia Aplicada [CEPEA] Esalq/USP. Os preços do mercado físico foram levantados junto a Secretária da Agricultura, Pecuária, Irrigação, Pesca e Aquicultura [SEAGRI-BA]. Foi calculada a correlação entre os preços nos mercados físico e futuro com o objetivo de saber o quanto a variação de um acompanha a variação do outro. Foram calculadas as bases para todos os dias do período de tempo em análise, em seguida foram encontrados a média e o desvio padrão da base. Encontrado o risco de base das operações de hedge, tendo como referência a tabela da distribuição normal-padrão, foram simulados contratos de compra e venda diariamente no período de um ano, utilizando o conceito de custo de base para determinar o preço objetivo, aumentando a segurança nas operações. Sugeriu-se na prática encerrar algumas posições e assumir outras à medida que o mercado se movimenta a favor ou contra a posição do hedge. Desta forma, estratégias hedge em mercados futuros se mostram como excelentes opções para se precaver contra a variação de preços de boi gordo.

22 March 2018 in Medicina Veterinária (UFRPE)
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WFWéverton José Lima Fonseca
Wéverton José Lima Fonseca
AEAmauri Felipe Evangelista
Amauri Felipe Evangelista
LBLaylson da Silva Borges
Laylson da Silva Borges
GVGleissa Mayone Silva Vogado
Gleissa Mayone Silva Vogado
Thales Lima SilvaThales Lima Silva
Thales Lima Silva
SJSeverino Cavalcante De Sousa Júnior
Severino Cavalcante De Sousa Júnior
Genetic evaluation studies in Tabapuã cattle breed using random regression models-Review