The study’s aim is to analyze the improved hand function and bimanual performance with unilateral cerebral palsy (CP) from repeat doses of an augmented, group-based pediatric constraint-induced movement therapy (pCIMT) camp. Fifteen children with unilateral CP (ages 5–15 years, 9 male, 6 female, Manual Abilities Classification System (MACS) I = 3, MACS II = 11, and MACS III = 1) participated in two sessions of an annual pCIMT camp. Participants attended 10 days of camp where they received group-based training wearing a constraint for a total of 50 h, received bilateral, occupation-based activities for 10 h (60 h total) including 30 min each day on the Hocoma Armeo^®Spring. The Assisting Hand Assessment (AHA) was administered pre-intervention and post-intervention. Our results discovered a mean interval dose 1 and 2 was 511 days. Dose 1 mean AHA score at baseline was 55.93 ± 12.78 and 63.07 ± 12.85 at post. Dose 2 mean AHA score as 58.13 ± 14.83 and post 66.53 ± 12.82. In conclusion, there was an overall significant bimanual functional improvement based on AHA scores that indicate, regardless of which camp session, scores improved from pre-intervention to post-intervention. There was a generalized upward trend in improved hand function of a group-based pCIMT, and diminished effects between doses were reversed with repeat doses.

To assess long-term changes in fathers' dietary intake and behaviors following a nutrition and physical activity program. Mexican-heritage fathers participated in a 6-week father-focused, family-centered program implemented in a border community. Promotoras used surveys to assess dietary intake of fruits and vegetables and healthy dietary behaviors at baseline (n = 42), program completion (n = 42), short-term (3-4 months postprogram, n = 24), and long-term (2.0-2.5 years postprogram, n = 36). Linear growth models tested changes in program outcomes. Fathers' dietary intake of fruits and vegetables and healthy dietary behavior scores significantly increased across time (P < 0.05). Education level had a moderating effect on growth in vegetable intake over time (β = -0.12; P = 0.002). A father-focused, family-centered approach may be one way to achieve lasting healthy dietary behavior changes in Latino fathers. Future researchers may consider alternative family structures (e.g., grandparent, single-parent) in program participation.

Researchers have long studied allostatic (over)load as an estimated measure of individual cumulative stress over a lifetime. Often called the overall ‘wear and tear’ from social and environmental stressors, allostatic (over)load shows promise as a practical indicator of general health trends in community settings. This data processing workflow aims to document our overall approach and reasoning when calculating allostatic (over)load for data analysis and knowledge sharing. The included repository features an R script for generating datasets using this workflow from the following data sources: All of Us Research Program data repository Health and Retirement Study (HRS) National Health and Nutrition Examination Survey (NHANES) Our allostatic (over)load measurement process, along with the linked repository, provides a reproducible workflow to process secondary data and offers insights into protocol-driven measurement practices in community environments.

Digital microscopy is increasingly used in veterinary diagnostic pathology. However, limited independent research has been published on its use, especially for the purpose of evaluating blood films. Hence, determining the potential limits of blood film assessments obtained via digital microscopy is needed. We compared the agreement of digital and optical cytology for the detection of common cellular morphology changes and abnormalities in veterinary blood films. Twenty-two veterinary clinical pathologists and residents evaluated canine, feline, and equine blood films on glass slides via optical microscopy and digitized blood film slides, with a ≥8-wk washout period between evaluations. One of the equine cases was a patient experimentally infected with Theileria haneyi . Using a standardized rubric, 16 erythrocyte features, 2 platelet features, and 2 leukocyte features were scored from absent to 4+. Additional comments at pathologist discretion were recorded. Changes in erythrocyte shape, platelets, and leukocytes were readily identified on both digital and glass slides. T. haneyi organisms were identified on significantly fewer digitized blood film slides than glass slides. Additionally, intra-observer consistency was low between digitized blood film slide and glass slide evaluation. Relative to glass slides, digitized blood film slides appear generally adequate for identifying erythrocyte, leukocyte, and platelet morphology changes, but may be inadequate for identifying intracellular T. haneyi organisms; however, more studies are needed. Clinicians should exercise caution when interpreting results from digitized blood film slides in which blood-borne infectious disease may be present.