I am a faculty member in the Basic Sciences Division of the Department of Pathology at Temple University. My research focuses on the pathogenesis and treatment of neuropsychiatric systemic lupus erythematosus (NPSLE), with a particular emphasis on inflammatory signaling pathways that drive disease progression. Since beginning my lupus research in 2004 as a postdoctoral fellow in the laboratory of Stefania Gallucci at Children's Hospital of Philadelphia, I have made important contributions to understanding Type I interferon signaling in systemic lupus and has identified novel molecular targets that attenuate these responses. My laboratory has also pioneered studies defining the role of the kallikrein-kinin system and its interaction with the renin-angiotensin system in regulating inflammation in systemic and neuropsychiatric lupus. Using in vivo, ex vivo, and in vitro models, my research integrates immunology, molecular biology, and behavioral studies to investigate depression, memory impairment, and anxiety in preclinical models of lupus, with the goal of identifying new therapeutic strategies for NPSLE.