The focus on emerging contaminants (ECs) in wastewater has intensified due to the considerable risks they present to human health and wildlife. This paper presents the results of the technical–economic assessment of the Clean Up solution, carried out in the framework of the project entitled “Validation of Adsorbent Materials and Advanced Oxidation Techniques to Remove Emerging Pollutants in Treated Wastewater”. The viability of the Clean Up system is evaluated by being applied as an advanced treatment system for treated urban wastewater, that is, for the elimination of pathogens and emerging pollutants (EPs), while considering the established quality criteria by current regulations. In this sense, it is a technology that has been successfully validated at an experimental level, and that offers similar removal performance compared to that of the most efficient alternatives available on the market. The technical–economic assessment has been conducted through a systematic process. Initially, the estimation involved the calculation of treatment costs for the Clean Up system when applied at an industrial scale. Subsequently, the treatment costs were estimated for the most favorable technological alternative to the Clean Up system from a technical–economic standpoint, also applied at an industrial scale, within identical scenarios and conditions as those assumed for the Clean Up system. The final step involved a comprehensive comparison of treatment costs between both alternatives, implemented uniformly under analogous conditions and assumed similar performance across all cases.

Emerging pollutants in wastewater pose significant risks to human health and wildlife, particularly due to their persistence in treated effluents from WWTPs. Very recent research has focused on developing new techniques based on advanced oxidation processes using inorganic and organic photocatalysts for treating polluted effluents under visible light. This study investigates a pesticide-removal system utilizing heterogeneous photoactive polymeric materials P2, P3, and P4. These materials, engineered as hydrophilic polymeric microparticles and functionalized with Rose Bengal, have demonstrated efficient singlet oxygen generation and first-order kinetics in the degradation of AHMPD, a pyrimidine fungicide. Given that most studies in the literature have concentrated on urban WWTPs, with less emphasis on industrial wastewater treatment, this research focused on real water samples from the effluent of an industrial WWTP in the agri-food sector, which processes large volumes of citrus and where high concentrations of AHMPD and other pesticides were detected at certain times of the year. The degradation potential of photoactive materials P3 and P4 was evaluated, achieving removal rates of AHMPD up to 85% under conditions of pH = 11 with 48 h of exposure to visible light.

Current sustainability challenges for the chemical industry include developing advanced wastewater treatment technologies and transitioning to renewable biomass for more sustainable processes. This study aims to design and develop photoactive colloidal microgels for environmental applications, focusing on the removal of pollutants and the green synthesis of sustainable materials. PNIPAM-based microgels with covalently integrated Rose Bengal as a photosensitizer was synthesized and characterized. The stimuli-responsive colloidal structure of the microgels enhances substrate adsorption and reaction kinetics, surpassing free Rose Bengal due to the local concentration effect provided by the polymeric matrix at the reaction temperature and pH. These materials, designed according to green chemistry principles, enable the sustainable synthesis of 5-hydroxy-2(5H)-furanone, a C4 building block intermediate, achieving over 99% conversion in aqueous media, which is a novel aspect compared to the literature. The removal of Diclofenac from wastewater has been highly efficient, reaching degradation rates of over 99% in 160 min. The photoactive microgels act as efficient photocatalysts, validated under direct solar irradiation, capable of generating singlet oxygen (O₂(¹Δg)) with full recoverability and reusability over multiple cycles. This approach provides a cost-effective eco-friendly solution to economic and environmental challenges in water treatment, as shown by scale-up economic simulations.

Previously synthesized and tested water-dispersible photoactive polymeric microparticles have been employed as heterogenous photosensitizers to evaluate their performance in generating singlet oxygen through direct solar irradiation. This study utilizes these photocatalysts for the degradation of Acetamiprid in IWWTP wastewater effluents from the Agri-food industry, exploring, in addition to direct or simulated solar irradiation, the influence of pH on the photooxidation process. Over a thousand emerging pollutants, including pesticides like Acetamiprid, have been detected in aquatic environments in recent years, posing challenges due to the limitations of current wastewater treatment technologies. The developed method is particularly effective under basic or slightly basic conditions, aligning with the natural pH of wastewater and addressing a limitation of conventional Acetamiprid degradation methods, which typically require medium acidification to be effective. Polymers P3 and P4 exhibited high photocatalytic activity, achieving over 99% degradation of Acetamiprid through oxidation via singlet oxygen generated by Rose Bengal supported on the polymer matrix, while maintaining catalytic efficiency across multiple cycles. The results confirm that Acetamiprid removal from industrial wastewater via direct solar irradiation is feasible, though constrained by the availability of sufficient effective sunlight hours.

Sustainability challenges faced by the chemical industry today include the increasing prevalence of persistent Contaminants of Emerging Concern in wastewater, which requires the development of advanced treatment technologies. Additionally, transitioning from petroleum-derived raw materials to renewable biomass is essential for achieving more sustainable chemical processes. PNIPAM microgels with covalently integrated Rose Bengal as a photosensitizer has been synthesized and characterized in this study. The micellar-like structure of the colloidal microgels enhances substrate adsorption and overall efficiency. Designed in alignment with Green Chemistry principles, these materials support sustainable applications such as the green synthesis of 5-hydroxy-2(5H)-furanone, a C4 building block intermediate, and the removal of Diclofenac from wastewater. These photoactive microgels act as efficient photocatalysts, capable of generating singlet oxygen (O₂(¹Δg)) under visible light, with full recoverability and reusability over multiple cycles. By employing direct solar-driven photocatalysis, the approach offers a cost-effective, eco-friendly solution to address economic and environmental challenges in water treatment processes, as demonstrated by scale-up economic simulations. Additionally, it allows the synthesis of 5-hydroxy-2(5H)-furanone in aqueous media, a sustainable key-factor enabled by the enhanced adsorption capabilities of the microgels.