In today’s multiprocessor systems-on-a-chip, the shared memory subsystem is a known source of temporal interference. The problem causes logically independent cores to affect each other’s performance, leading to pessimistic worst-case execution time analysis. Memory regulation via throttling is one of the most practical techniques to mitigate interference. Traditional regulation schemes rely on a combination of timer and performance counter interrupts to be delivered and processed on the same cores running real-time workload. Unfortunately, to prevent excessive overhead, regulation can only be enforced at a millisecond-scale granularity. In this work, we present a novel regulation mechanism from outside the cores that monitors performance counters for the application core’s activity in main memory at a microsecond scale. The approach is fully transparent to the applications on the cores, and can be implemented using widely available on-chip debug facilities. The presented mechanism also allows more complex composition of metrics to enact load-aware regulation. For instance, it allows redistributing unused bandwidth between cores while keeping the overall memory bandwidth of all cores below a given threshold. We implement our approach on a host of embedded platforms and conduct an in-depth evaluation on the Xilinx Zynq UltraScale+ ZCU102, NXP i.MX8M and NXP S32G2 platforms using the San Diego Vision Benchmark Suite.

Gulf War illness (GWI) refers to the multitude of chronic health symptoms, spanning from fatigue, musculoskeletal pain, and neurological complaints to respiratory, gastrointestinal, and dermatologic symptoms experienced by about 250,000 GW veterans who served in the 1991 Gulf War (GW). Longitudinal studies showed that the severity of these symptoms often remain unchanged even years after the GW, and these veterans with GWI continue to have poorer general health and increased chronic medical conditions than their non-deployed counterparts. For better management and treatment of this condition, there is an urgent need for developing objective biomarkers that can help with simple and accurate diagnosis of GWI. In this study, we applied multiple neuroimaging techniques, including T1-weighted magnetic resonance imaging (T1W-MRI), diffusion tensor imaging (DTI), and novel neurite density imaging (NDI) to perform both a group-level statistical comparison and a single-subject level machine learning (ML) analysis to identify diagnostic imaging features of GWI. Our results supported NDI as the most sensitive in defining GWI characteristics. In particular, our classifier trained with white matter NDI features achieved an accuracy of 90% and F-score of 0.941 for classifying GWI cases from controls after the cross-validation. These results are consistent with our previous study which suggests that NDI measures are sensitive to the microstructural and macrostructural changes in the brain of veterans with GWI, which can be valuable for designing better diagnosis method and treatment efficacy studies.