Wen Xu

Ms. Wen Xu

University of Nottingham Ningbo China
orcid

Research Focus & Metrics

Academic Career Length

6Years (2021-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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4 January 2023 in International Journal of Social Psychiatry
Verified
Journal Article
Closed access
WXWen Xu
Wen Xu
Iuliia PavlovaIuliia Pavlova
Iuliia Pavlova
XCXi Chen
Xi Chen
Petro PetrytsaPetro Petrytsa
Petro Petrytsa
LGLorenz Graf-Vlachy
Lorenz Graf-Vlachy
SZStephen Zhang
Stephen Zhang
Context: The Russian attack on Ukraine has been ongoing since February 24, 2022. Nevertheless, no research has documented the mental health of Ukrainians during the biggest land war in Europe after the Second World War, or how Ukrainians cope with the impact of the war. Objectives: To provide the prevalence rates of symptoms of psychological distress, anxiety, depression, and insomnia; and to link them with Ukrainians’ productive coping strategies during the war. Design, setting, and participants: Online survey conducted in Ukraine during the initial period of the Russian invasion (March 19–31, 2022), using a quota sampling method, of 1,400 Ukrainians aged 18 years or older, with a total of 801 valid responses for a response rate of 57.2%. Main outcome measures: Psychological distress assessed by the Kessler Psychological Distress scale (K6); anxiety assessed by Generalized Anxiety Disorder-2 (GAD-2) scale; depression assessed by Patient Health Questionnaire-2 (PHQ-2); insomnia assessed by Insomnia Severity Index-4 (ISI-4); modes of coping assessed by Brief COPE. Results: Of 801 Ukrainian adults, 52.7% had symptoms of psychological distress (mean = 13.3 [ SD = 4.9]); 54.1% of them reported symptoms of anxiety (mean = 2.9 [ SD = 1.7]); 46.8% reported symptoms of depression (mean = 2.6 [ SD = 1.6]). Symptom criteria for insomnia were met by 97 respondents (12.1%) (mean = 10.4 [ SD = 4.2]). Demographic variables (including gender, living in an urban area, having children or elderly persons in the household, living in an area occupied by Russian forces) were associated with symptoms of distress, anxiety, depression, and insomnia. The productive coping strategies of using instrumental support, behavioral disengagement, self-distraction, and planning were significantly associated with mental health symptoms. Conclusions: Prevalence rates of symptoms of psychological distress, anxiety, depression, and insomnia were high. These findings underscore the need for healthcare and productive coping strategies for Ukrainians during the war.

JCJiyao Chen
Jiyao Chen
NFNusrat Farah
Nusrat Farah
Rebecca Kechen DONGRebecca Kechen DONG
Rebecca Kechen DONG
RCRichard Chen
Richard Chen
WXWen Xu
Wen Xu
SZStephen Zhang
Stephen Zhang
We aim to provide a systematic review and meta-analysis of the prevalence rates of mental health symptoms among major African populations during the COVID-19 pandemic. We include articles from PubMed, Embase, Web of Science, PsycINFO, and medRxiv between 1 February 2020 and 6 February 2021, and pooled data using random-effects meta-analyses. We identify 28 studies and 32 independent samples from 12 African countries with a total of 15,071 participants. The pooled prevalence of anxiety was 37% in 27 studies, of depression was 45% in 24 studies, and of insomnia was 28% in 9 studies. The pooled prevalence rates of anxiety, depression, and insomnia in North Africa (44%, 55%, and 31%, respectively) are higher than those in Sub-Saharan Africa (31%, 30%, and 24%, respectively). We find (a) a scarcity of studies in several African countries with a high number of COVID-19 cases; (b) high heterogeneity among the studies; (c) the extent and pattern of prevalence of mental health symptoms in Africa is high and differs from elsewhere—more African adults suffer from depression rather than anxiety and insomnia during COVID 19 compared to adult populations in other countries/regions. Hence, our findings carry crucial implications and impact future research to enable evidence-based medicine in Africa.

19 April 2022 in Epidemiology and Psychiatric Sciences
Verified
Journal Article
Open access
PDF file
SZStephen Zhang
Stephen Zhang
KBKavita Batra
Kavita Batra
WXWen Xu
Wen Xu
TLTao Liu
Tao Liu
Rebecca Kechen DONGRebecca Kechen DONG
Rebecca Kechen DONG
JCJiyao Chen
Jiyao Chen
Aims: There is a lack of evidence related to the prevalence of mental health symptoms as well as their heterogeneities during the coronavirus disease 2019 (COVID-19) pandemic in Latin America, a large area spanning the equator. The current study aims to provide meta-analytical evidence on mental health symptoms during COVID-19 among frontline healthcare workers, general healthcare workers, the general population and university students in Latin America.Methods: Bibliographical databases, such asPubMed, Embase, Web of Science, PsycINFOandmedRxiv, were systematically searched to identify pertinent studies up to August 13, 2021. Two coders performed the screening using predefined eligibility criteria. Studies were assigned quality scores using the Mixed Methods Appraisal Tool. The double data extraction method was used to minimise data entry errors.Results: A total of 62 studies with 196 950 participants in Latin America were identified. The pooled prevalence of anxiety, depression, distress and insomnia was 35%, 35%, 32% and 35%, respectively. There was a higher prevalence of mental health symptoms in South America compared to Central America (36%v. 28%,p< 0.001), in countries speaking Portuguese (40%)v.Spanish (30%). The pooled prevalence of mental health symptoms in the general population, general healthcare workers, frontline healthcare workers and students in Latin America was 37%, 34%, 33% and 45%, respectively.Conclusions: The high yet heterogenous level of prevalence of mental health symptoms emphasises the need for appropriate identification of psychological interventions in Latin America.

26 November 2021 in Psychiatry and Clinical Neurosciences
Verified
Journal Article
Open access
PDF file
SPSofia Pappa
Sofia Pappa
JCJiyao Chen
Jiyao Chen
JBJoshua Barnett
Joshua Barnett
ACAnabel Chang
Anabel Chang
Rebecca Kechen DONGRebecca Kechen DONG
Rebecca Kechen DONG
SZStephen Zhang
Stephen Zhang
Aims: The Covid‐19 pandemic has had a substantial impact on the mental health of the general public and high‐risk groups worldwide. Due to its proximity and close links to China, Southeast Asia was one of the first regions to be affected by the outbreak. The aim of this systematic review was to evaluate the prevalence of anxiety, depression and insomnia in the general adult population and healthcare workers (HCWs) in Southeast Asia during the course of the first year of the pandemic.Methods: Several literature databases were systemically searched for articles published up to February 2021 and two reviewers independently evaluated all relevant studies using pre‐determined criteria. The prevalence rates of mental health symptoms were calculated using a random‐effect meta‐analysis model.Results: In total, 32 samples from 25 studies with 20 352 participants were included. Anxiety was assessed in all 25 studies and depression in 15 studies with pooled prevalence rates of 22% and 16%, respectively. Only two studies assessed insomnia, which was estimated at 19%. The prevalence of anxiety and depression was similar among frontline HCWs (18%), general HCWs (17%), and students (20%) while being noticeably higher in the general population (27%).Conclusions: This is the first systematic review to investigate the mental health impact of the Covid‐19 pandemic in Southeast Asia. A considerable proportion of the general population and HCWs reported mild to moderate symptoms of anxiety and depression; the pooled prevalence rater, however, remain significantly lower than those reported in other areas such as China and Europe.

SZStephen Zhang
Stephen Zhang
RCRichard Chen
Richard Chen
WXWen Xu
Wen Xu
AYAllen Yin
Allen Yin
Rebecca Kechen DONGRebecca Kechen DONG
Rebecca Kechen DONG
XWXue Wan
Xue Wan
Background: General population, frontline healthcare workers (HCWs), and adult students in Spain are at risk of anxiety, depression, and insomnia symptoms during the COVID-19 crisis. A meta-analysis of the individual studies on these symptoms would provide systematic evidence to aid policymakers and researchers in focusing on prevalence, risk, and best interventions. Objective: This paper aims to be the first meta-analysis and systematic review to calculate the prevalence of anxiety, depression, and insomnia symptoms in Spain’s adult population (general population, frontline healthcare workers (HCWs), and adult students) during the Covid-19 epidemic. Method: Random-effect meta-analysis was used to estimate the prevalence of anxiety, depression, and insomnia. Results: The meta-analysis includes 28 studies with 38 individual samples in Spain. The pooled prevalence of anxiety symptoms in 22 studies comprising a sample population of 82,024 was 20% (95% CI: 15–25%), that of depression symptoms in 22 articles with a total sample comprising 82,890 individuals was 22% (95% CI: 18–28%), and that of insomnia symptoms in three articles with a sample population of 745 was 57% (95% CI: 48–66%. Conclusions: The accumulative evidence reveals that adults in Spain suffered higher prevalence rates of mental symptoms during the COVID-19 crisis, with a significantly higher rate relative to other countries such as China. Our synthesis also reveals a relative lack of studies on frontline and general HCWs in Spain.

20 April 2021 in medRxiv
Verified
Preprint
Open access
PDF file
JCJiyao Chen
Jiyao Chen
NFNusrat Farah
Nusrat Farah
Rebecca Kechen DONGRebecca Kechen DONG
Rebecca Kechen DONG
RCRichard Chen
Richard Chen
WXWen Xu
Wen Xu
SZStephen Zhang
Stephen Zhang
Objective: In this paper, we aim to provide a systematic review and meta-analysis on the prevalence rates of mental health symptoms of anxiety, depression, and insomnia among the major populations during the COVID-19 pandemic in Africa. Design: A systematic review and meta-analysis. Data sources: We search and include articles using PubMed, Embase, Web of Science, PsycINFO, and medRxiv databases between Feb 202 and Feb 6th, 2021. Eligibility criteria and data analysis: The meta-analysis targets the prevalence rates of mental health symptoms of major populations including frontline/general healthcare workers (HCWs), the general adult population, and medical students during the COVID-19 pandemic in Africa. To estimate the prevalence rates of anxiety, depression, and insomnia, we pooled data using random-effects meta-analyses. Results: In this meta-analysis, we identify and include 28 studies and 32 independent samples from 12 countries with a total of 15,072 participants in Africa. Ethiopia (7) and Egypt (6) had the largest number of studies. While many countries including, but not limited to, Algeria, Kenya, and Ghana had a high number of COVID-19 cases, as many as three quarters of African countries have no studies. The pooled prevalence of anxiety in 27 studies was 37% (95%CI: 31-43%, I 2 = 99.0%) and that of depression in 24 studies was 45% (95%CI: 36-51%, I 2 = 99.5%) and that of insomnia in 9 studies was 28% (95%CI: 20-41%, I 2 = 99.2%). The pooled prevalence rates of anxiety, depression, and insomnia in North Africa (44%, 55%, and 31%, respectively) are higher than the rates in Sub-Saharan Africa (31%, 30%, and 24%, respectively). Our analysis indicated high heterogeneity and varying prevalence rates of mental health symptoms during the COVID-19 pandemic in Africa. Discussion: We discuss our findings that a) a scarcity of studies in several African countries with a high number of COVID-19 cases, b) high heterogeneity among the studies, c) the extent of prevalence of mental health symptoms in Africa to be high, and d) the pattern of mental health symptoms in Africa differs from elsewhere, i.e., more African adults suffer from depression rather than anxiety and insomnia during COVID 19 compared to adult population in other countries or regions. Hence, our findings carry crucial implications for healthcare organizations and future research to enable evidence-based medicine in Africa. Our findings also call for increased scholarly attention on Africa, the least studied continent with a limited amount of research on mental health symptoms under the COVID 19 pandemic. Trial registration: CRD42020224458