Dr. Yang has a long-standing dedication to research in probiotics and the gut microbiota. His primary research interests encompass: (1) the development and clinical translation of functional synthetic microbiome preparations, particularly probiotic-based formulations; (2) the elucidation of host-microbiota interaction mechanisms; and (3) the targeted screening, development, and clinical application of both traditional probiotics and human-derived next-generation probiotics (NGPs).