The aim of this study is to evaluate if Kinect is a valid and reliable clinical gait analysis tool for children with cerebral palsy (CP), and whether linear regression and long short-term memory (LSTM) recurrent neural network methods can improve its performance. A gait analysis was conducted on ten children with CP, on two occasions. Lower limb joint kinematics computed from the Kinect and a traditional marker-based Motion Analysis system were investigated by calculating the root mean square errors (RMSE), the coefficients of multiple correlation (CMC), and the intra-class correlation coefficients (ICC_2,k). Results showed that the Kinect-based kinematics had an overall modest to poor correlation (CMC—less than 0.001 to 0.70) and an angle pattern similarity with Motion Analysis. After the calibration, RMSE on every degree of freedom decreased. The two calibration methods indicated similar levels of improvement in hip sagittal (CMC—0.81 ± 0.10 vs. 0.75 ± 0.22)/frontal (CMC—0.41 ± 0.35 vs. 0.42 ± 0.37) and knee sagittal kinematics (CMC—0.85±0.07 vs. 0.87 ± 0.12). The hip sagittal (CMC—0.97±0.05) and knee sagittal (CMC—0.88 ± 0.12) angle patterns showed a very good agreement over two days. Modest to excellent reliability (ICC_2,k—0.45 to 0.93) for most parameters renders it feasible for observing ongoing changes in gait kinematics.

Children with cerebral palsy (CP) have high risks of falling. It is necessary to evaluate gait stability for children with CP. In comparison to traditional motion capture techniques, the Kinect has the potential to be utilised as a cost-effective gait stability assessment tool, ensuring frequent and uninterrupted gait monitoring. To evaluate the validity and reliability of this measurement, in this study, ten children with CP performed two testing sessions, of which gait data were recorded by a Kinect V2 sensor and a referential Motion Analysis system. The margin of stability (MOS) and gait spatiotemporal metrics were examined. For the spatiotemporal parameters, intraclass correlation coefficient (ICC_2,k) values were from 0.83 to 0.99 between two devices and from 0.78 to 0.88 between two testing sessions. For the MOS outcomes, ICC_2,k values ranged from 0.42 to 0.99 between two devices and 0.28 to 0.69 between two test sessions. The Kinect V2 was able to provide valid and reliable spatiotemporal gait parameters, and it could also offer accurate outcome measures for the minimum MOS. The reliability of the Kinect V2 when assessing time-specific MOS variables was limited. The Kinect V2 shows the potential to be used as a cost-effective tool for CP gait stability assessment.

In healthcare, digital therapeutics provides users with better services in terms of preventing, managing and treating diseases. However, it is a non-trivial task to ensure the security of digital therapeutics. In some scenarios, for example, the wearable biosensors might be used by others or violated by malicious adversaries. When these happen, the patient’s treatment might be affected. Investigation shows that conventional one-time login authentication mechanism cannot solve the above problems. Motivated by these observations, in this paper we present a continuous authentication scheme for digital therapeutics using denoising autoencoder. Specifically, it achieves user-transparent re-authentication when users wear the wearable devices. To improve the re-authentication rate, the denoising autoencoder is employed to learn gait features using three-axis acceleration data. To illustrate the practicality, we evaluate the performance of our scheme using public datasets and compare it with that of relevant schemes. The results show that the re-authentication rate of our scheme reaches 92.8%, and it works well no matter users’ activities (walking, sitting, running and/or jumping, etc).