Cancer is the second leading cause of death worldwide, and the death rate of lung cancer is much higher than other types of cancers. In recent years, numerous novel computer-aided diagnostic techniques with deep learning have been designed to detect lung cancer in early stages. However, deep learning models are easy to overfit, and the overfitting problem always causes lower performance. To solve this problem of lung cancer classification tasks, we proposed a hybrid framework called LCGANT. Specifically, our framework contains two main parts. The first part is a lung cancer deep convolutional GAN (LCGAN) to generate synthetic lung cancer images. The second part is a regularization enhanced transfer learning model called VGG-DF to classify lung cancer images into three classes. Our framework achieves a result of $99.84\%\pm 0.156\%$ (accuracy), $99.84\%\pm 0.153\%$ (precision), $99.84\%\pm 0.156\%$ (sensitivity), and $99.84\%\pm 0.156\%$ (F1-score). The result reaches the highest performance of the dataset for the lung cancer classification task. The proposed framework resolves the overfitting problem for lung cancer classification tasks, and it achieves better performance than other state-of-the-art methods.

Goal: Deep learning techniques have made significant progress in medical image analysis. However, obtaining ground truth labels for unlabeled medical images is challenging as they often outnumber labeled images. Thus, training a high-performance model with limited labeled data has become a crucial challenge. Methods: This study introduces an underlying knowledge-based semi-supervised framework called UKSSL, consisting of two components: MedCLR extracts feature representations from the unlabeled dataset; UKMLP utilizes the representation and fine-tunes it with the limited labeled dataset to classify the medical images. Results: UKSSL evaluates on the LC25000 and BCCD datasets, using only 50% labeled data. It gets precision, recall, F1-score, and accuracy of 98.9% on LC25000 and 94.3%, 94.5%, 94.3%, and 94.1% on BCCD, respectively. These results outperform other supervised-learning methods using 100% labeled data. Conclusions : The UKSSL can efficiently extract underlying knowledge from the unlabeled dataset and perform better using limited labeled medical images.

Objective: The only possible solution to increase the patients’ fatality rate is lung cancer early-stage detection. Recently, deep learning techniques became the most promising methods in medical image analysis compared with other numerous computer-aided diagnostic techniques. However, deep learning models always get lower performance when the model is overfitting. Methods: We present a Lung Cancer Data Augmented Ensemble (LCDAE) framework to solve the overfitting and lower performance problems in the lung cancer classification tasks. The LCDAE has 3 parts: The Lung Cancer Deep Convolutional GAN, which can synthesize images of lung cancer; A Data Augmented Ensemble model (DA-ENM), which ensembled 6 fine-tuned transfer learning models for training, testing, and validating on a lung cancer dataset; The third part is a Hybrid Data Augmentation (HDA) which combines all the data augmentation techniques in the LCDAE. Results: By comparing with existing state-of-the-art methods, the LCDAE obtains the best accuracy of 99.99%, the precision of 99.99%, and the F1-score of 99.99%. Conclusion: Our proposed LCDAE can overcome the overfitting issue for the lung cancer classification tasks by applying different data augmentation techniques, our method also has the best performance compared to state-of-the-art approaches.

Fully supervised learning methods necessitate a substantial volume of labelled training instances, a process that is typically both labour-intensive and costly. In the realm of medical image analysis, this issue is further amplified, as annotated medical images are considerably more scarce than their unlabelled counterparts. Consequently, leveraging unlabelled images to extract meaningful underlying knowledge presents a formidable challenge in medical image analysis. This paper introduces a simple triple-view unsupervised representation learning model (SimTrip) combined with a triple-view architecture and loss function, aiming to learn meaningful inherent knowledge efficiently from unlabelled data with small batch size. With the meaningful representation extracted from unlabelled data, our model demonstrates exemplary performance across two medical image datasets. It achieves this using only partial labels and outperforms other state-of-the-art methods. The method we present herein offers a novel paradigm for unsupervised representation learning, establishing a baseline that is poised to inspire the development of more intricate SimTrip-based methods across a spectrum of computer vision applications. Code and user guide are released at https://github.com/JerryRollingUp/SimTripSystem, the system also runs at http://43.131.9.159:5000/.

Background: Blood is responsible for delivering nutrients to various organs, which store important health information about the human body. Therefore, the diagnosis of blood can indirectly help doctors judge a person’s physical state. Recently, researchers have applied deep learning (DL) to the automatic analysis of blood cells. However, there are still some deficiencies in these models. Methods: To cope with these issues, we propose a novel network for the multi-classification of blood cells, which is called DLBCNet. A new specifical model for blood cells (BCGAN) is designed to generate synthetic images. The pre-trained ResNet50 is implemented as the backbone model, which serves as the feature extractor. The extracted features are fed to the proposed ETRN to improve the multi-classification performance of blood cells. Results: The average accuracy, average sensitivity, average precision, average specificity, and average f1-score of the proposed model are 95.05%, 93.25%, 97.75%, 93.72%, and 95.38%, accordingly. Conclusions: The performance of the proposed model surpasses other state-of-the-art methods in reported classification results.

Recently, large language models such as ChatGPT have made huge strides in understanding and generating human-like text and have demonstrated considerable success in natural language processing. These foundation models also perform well in computer vision. However, there is a growing need to use these technologies for specific medical tasks, especially for identifying cancer in images. This paper looks at how these foundation models, such as the segment anything model, could be used for cancer segmentation, discussing the potential benefits and challenges of applying large foundation models to help with cancer diagnoses.