Background: This study aimed to investigate the intricate relationship among treatment adherence, the light triad of personality, self-coherence, and psychological well-being in individuals diagnosed with Type 2 Diabetes Mellitus (T2DM). Structural equation modeling (SEM) was employed to elucidate the direct and mediated pathways linking these variables, while network analysis sought to identify and characterize the underlying factors of the light triad of personality within the context of T2DM management. Method: A path analysis-network analysis study using convenience sampling was conducted, recruiting 412 T2DM patients from ten private practices and general hospitals in Gilan province, Iran. Data collection utilized Antonovsky's Self of Coherence scale (SOC), The Light Triad Rating Scale, and The Reef's Psychological Well-being Questionnaire. Structural equation modeling assessed model fitness and determined direct and indirect links between variables. Analysis was conducted using R-Studio software (Version 4.2.1), SPSS (V.26), and AMOS software (V.24). Results: Confirmatory factor analysis and network analysis confirmed the three-factor structure of the Light Triad of Personality scale. Direct impacts of Light Triad of Personality (β = 0.34, p < .001) and self-coherence (β = 0.32, p < .001) on treatment adherence were observed. Psychological well-being played an indirect role in this relationship, with significant effects from Light Triad of Personality (β = 0.25, p < .001) and self-coherence (β = 0.08, p < .001) on treatment adherence. Bootstrapped exploratory graph analysis revealed an average of 3 dimensions within the network, indicating community structures. Conclusion: SEM analysis demonstrated good model fit, suggesting the importance of designing interventional programs incorporating self-coherence and psychological well-being frameworks to enhance treatment adherence in T2DM patients.

Mohammadreza Kordbagheri; Seyedeh Masoumeh Bagheri; Nasrin Jalali Heris; Parisa Matbouraftar; Mozhdeh Azarian; Seyedeh Maryam Mousavi. The mediating role of psychological well-being in the relationship between the light triad of personality and sense of concordance with treatment adherence in patients with type 2 diabetes: A network analysis and structural equation modeling study. Acta Psychologica 2024, 248, 104361 .

Mohammadreza Kordbagheri, Seyedeh Masoumeh Bagheri, Nasrin Jalali Heris, Parisa Matbouraftar, Mozhdeh Azarian, Seyedeh Maryam Mousavi. The mediating role of psychological well-being in the relationship between the light triad of personality and sense of concordance with treatment adherence in patients with type 2 diabetes: A network analysis and structural equation modeling study. Acta Psychologica. 2024; 248 ():104361.

Mohammadreza Kordbagheri; Seyedeh Masoumeh Bagheri; Nasrin Jalali Heris; Parisa Matbouraftar; Mozhdeh Azarian; Seyedeh Maryam Mousavi. 2024. "The mediating role of psychological well-being in the relationship between the light triad of personality and sense of concordance with treatment adherence in patients with type 2 diabetes: A network analysis and structural equation modeling study." Acta Psychologica 248, no. : 104361.

Marcos Tostado-Véliz; Ahmad Rezaee Jordehi; Seyed Amir Mansouri; Antonio Escámez; Yahya Z. Alharthi; Francisco Jurado. Risk-averse electrolyser sizing in industrial parks: An efficient stochastic-robust approach. Applied Energy 2024, 367 .

Marcos Tostado-Véliz, Ahmad Rezaee Jordehi, Seyed Amir Mansouri, Antonio Escámez, Yahya Z. Alharthi, Francisco Jurado. Risk-averse electrolyser sizing in industrial parks: An efficient stochastic-robust approach. Applied Energy. 2024; 367 ():.

Marcos Tostado-Véliz; Ahmad Rezaee Jordehi; Seyed Amir Mansouri; Antonio Escámez; Yahya Z. Alharthi; Francisco Jurado. 2024. "Risk-averse electrolyser sizing in industrial parks: An efficient stochastic-robust approach." Applied Energy 367, no. : .

Introduction: Aging and obesity have common symptoms, including glucose and lipid metabolism changes. Activation of sirtuin 1 and FOXO1 (Forkhead Box Protein O1) can positively affect metabolic disorders associated with aging and obesity. This research aimed to investigate 16 weeks of combined exercise on the plasma levels of sirtuin 1, FOXO1, and glucose homeostasis in obese elderly. Methods: 40 obese elderly men with an average age of 61.90 ± 2.84 were selected and randomly divided into two experimental and control groups. The participants trained three days a week (each session 90 minutes) for 16 weeks. 48 hours before and after exercise, anthropometric characteristics and plasma values of sirtuin 1, FOXO1, fasting blood sugar, insulin, HOMA-IR (Homeostatic Model Assessment for Insulin Resistance), and HOMA-B (Homeostasis Model Assessment of β-Cell) were taken from the samples and measured by ELISA method. Data analysis was done using SPSS 16 software, independent and dependent t-tests at a significance level of P˂ 0.05. Results: Levels of fasting blood sugar (P=0.04), and insulin (P=0.008) in the experimental group decreased significantly compared to the control group, while the serum levels of sirtuin1 (P=0.0001) and FOXO1 (P=0.0001) had a significant increase. Correlated t results in the experimental group showed a significant decrease in insulin, HOMA-IR, and HOMA-B (P = 0.001) and a significant increase in the serum levels of sirtuin1 (P = 0.0001) and FOXO1 (P = 0.0001) (P ˂ 0.05). Conclusion: Based on the results of this study, it seems that 16 weeks of combined training has a favorable effect on improving glucose homeostasis, increasing sirtuin 1 and FOXO1 levels in elderly obese men.

Maryam Safari; Ramin Shabani; Mohammad Reza Fadaei. Effect of Combined Exercises on Glucose Homeostasis and Plasma Levels of Sirtuin 1 and FOXO1 in Obese Elderly Men. Journal of Shahid Sadoughi University of Medical Sciences 2024 .

Maryam Safari, Ramin Shabani, Mohammad Reza Fadaei. Effect of Combined Exercises on Glucose Homeostasis and Plasma Levels of Sirtuin 1 and FOXO1 in Obese Elderly Men. Journal of Shahid Sadoughi University of Medical Sciences. 2024; ():.

Maryam Safari; Ramin Shabani; Mohammad Reza Fadaei. 2024. "Effect of Combined Exercises on Glucose Homeostasis and Plasma Levels of Sirtuin 1 and FOXO1 in Obese Elderly Men." Journal of Shahid Sadoughi University of Medical Sciences , no. : .