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Few studies have investigated the associations between outdoor air pollution and outpatient visits for respiratory diseases (RDs) in general population. We collected daily outpatient data of primary RDs from five hospitals in Jinan during January 2012 and December 2016, as well as daily measurements of air pollutants from the Jinan Environmental Monitoring Center and daily meteorological variables from the China Meteorological Data Sharing Service System. A generalized additive model (GAM) with quasi-Poisson regression was constructed to estimate the associations between daily average concentrations of outdoor air pollutants (PM2.5,PM10, SO2, NO2, CO and O3) and daily outpatient visits of RDs after adjusting for long-time trends, seasonality, the “day of the week” effect, and weather conditions. Subgroup analysis stratified by gender, age group and the type of RDs was conducted. A total of 1,373,658 outpatient visits for RDs were identified. Increases of 10 μg/m3 in PM2.5, PM10, NO2, CO and O3 were associated with0.168% (95% CI, 0.072–0.265%), 0.149% (95% CI, 0.082–0.215%), 0.527% (95% CI, 0.211–0.843%), 0.013% (95% CI, 0.003–0.023%), and 0.189% (95% CI, 0.032–0.347%) increases in daily outpatient visits for RDs, respectively. PM2.5 and PM10 showed instant and continuous effects, while NO2, CO and O3 showed delayed effects on outpatient visits for RDs. In stratification analysis, PM2.5 and PM10 were associated with acute RDs only. Exposure to outdoor air pollutants including PM2.5, PM10, NO2, CO and O3 associated with increased risk of outpatient visits for RDs.
Shanshan Wang; Yifan Li; Aimin Niu; Yao Liu; Lili Su; Wanmei Song; Jinyue Liu; Yunxia Liu; Huaichen Li. The impact of outdoor air pollutants on outpatient visits for respiratory diseases during 2012–2016 in Jinan, China. Respiratory Research 2018, 19, 1 -8.
AMA StyleShanshan Wang, Yifan Li, Aimin Niu, Yao Liu, Lili Su, Wanmei Song, Jinyue Liu, Yunxia Liu, Huaichen Li. The impact of outdoor air pollutants on outpatient visits for respiratory diseases during 2012–2016 in Jinan, China. Respiratory Research. 2018; 19 (1):1-8.
Chicago/Turabian StyleShanshan Wang; Yifan Li; Aimin Niu; Yao Liu; Lili Su; Wanmei Song; Jinyue Liu; Yunxia Liu; Huaichen Li. 2018. "The impact of outdoor air pollutants on outpatient visits for respiratory diseases during 2012–2016 in Jinan, China." Respiratory Research 19, no. 1: 1-8.
We investigate the structural stability, mobility and electronic properties of typical point defects in 2D arsenene, antimonene and antimony arsenide.
Xiaotian Sun; Yunxia Liu; Zhigang Song; Yongdan Li; Weizhou Wang; Haiping Lin; Lu Wang; Youyong Li. Structures, mobility and electronic properties of point defects in arsenene, antimonene and an antimony arsenide alloy. Journal of Materials Chemistry C 2017, 5, 4159 -4166.
AMA StyleXiaotian Sun, Yunxia Liu, Zhigang Song, Yongdan Li, Weizhou Wang, Haiping Lin, Lu Wang, Youyong Li. Structures, mobility and electronic properties of point defects in arsenene, antimonene and an antimony arsenide alloy. Journal of Materials Chemistry C. 2017; 5 (17):4159-4166.
Chicago/Turabian StyleXiaotian Sun; Yunxia Liu; Zhigang Song; Yongdan Li; Weizhou Wang; Haiping Lin; Lu Wang; Youyong Li. 2017. "Structures, mobility and electronic properties of point defects in arsenene, antimonene and an antimony arsenide alloy." Journal of Materials Chemistry C 5, no. 17: 4159-4166.
Hand, foot and mouth disease (HFMD) has been a substantial burden throughout the Asia-Pacific countries over the past decades. For the purposes of disease prevention and climate change health impact assessment, it is important to understand the temperature–disease association for HFMD in different geographical locations. This study aims to assess the impact of temperature on HFMD incidence in an inland city and a coastal city and investigate the heterogeneity of temperature–disease associations. Daily morbidity data and meteorological variables of the study areas were collected for the period from 2007 to 2012. A total of 108,377 HFMD cases were included in this study. A distributed lag non-linear model (DLNM) with Poisson distribution was used to examine the nonlinear lagged effects of daily mean temperature on HFMD incidence. After controlling potential confounders, temperature showed significant association with HFMD incidence and the two cities demonstrated different impact modes ( I2= 96.1%; p < 0.01). The results highlight the effect of temperature on HFMD incidence and the impact pattern may be modified by geographical localities. Our findings can be a practical reference for the early warning and intervention strategies of HFMD.
Lin Zhu; Zhongshang Yuan; Xianjun Wang; Jie Li; Lu Wang; Yunxia Liu; Fuzhong Xue; Yanxun Liu. The Impact of Ambient Temperature on Childhood HFMD Incidence in Inland and Coastal Area: A Two-City Study in Shandong Province, China. International Journal of Environmental Research and Public Health 2015, 12, 8691 -8704.
AMA StyleLin Zhu, Zhongshang Yuan, Xianjun Wang, Jie Li, Lu Wang, Yunxia Liu, Fuzhong Xue, Yanxun Liu. The Impact of Ambient Temperature on Childhood HFMD Incidence in Inland and Coastal Area: A Two-City Study in Shandong Province, China. International Journal of Environmental Research and Public Health. 2015; 12 (8):8691-8704.
Chicago/Turabian StyleLin Zhu; Zhongshang Yuan; Xianjun Wang; Jie Li; Lu Wang; Yunxia Liu; Fuzhong Xue; Yanxun Liu. 2015. "The Impact of Ambient Temperature on Childhood HFMD Incidence in Inland and Coastal Area: A Two-City Study in Shandong Province, China." International Journal of Environmental Research and Public Health 12, no. 8: 8691-8704.
The aim of this study was to quantify the relationship between meteorological factors and the occurrence of hand, foot, and mouth disease (HFMD) among children in Shandong Province, China, at a county level, using spatial panel data models.Descriptive analysis was applied to describe the epidemic characteristics of HFMD from January 2008 to December 2012, and then a global autocorrelation statistic (Moran's I) was used to detect the spatial autocorrelation of HFMD in each year. Finally, spatial panel data models were performed to explore the association between the incidence of HFMD and meteorological factors.Moran's I at the county level were high, from 0.30 to 0.45 (p < 0.001), indicating the existence of a high spatial autocorrelation on HFMD. Spatial panel data models are more appropriate to describe the data. Results showed that the incidences of HFMD in Shandong Province, China were significantly associated with average temperature, relative humidity, vapor pressure, and wind speed.Spatial panel data models are useful when longitudinal data with multiple units are available and spatial autocorrelation exists. The association found between HFMD and meteorological factors makes a contribution towards advancing knowledge with respect to the causality of HFMD and has policy implications for HFMD prevention and control.
Hao Wang; Zhaohui Du; Xianjun Wang; Yunxia Liu; Zhongshang Yuan; Yanxun Liu; Fuzhong Xue. Detecting the association between meteorological factors and hand, foot, and mouth disease using spatial panel data models. International Journal of Infectious Diseases 2015, 34, 66 -70.
AMA StyleHao Wang, Zhaohui Du, Xianjun Wang, Yunxia Liu, Zhongshang Yuan, Yanxun Liu, Fuzhong Xue. Detecting the association between meteorological factors and hand, foot, and mouth disease using spatial panel data models. International Journal of Infectious Diseases. 2015; 34 ():66-70.
Chicago/Turabian StyleHao Wang; Zhaohui Du; Xianjun Wang; Yunxia Liu; Zhongshang Yuan; Yanxun Liu; Fuzhong Xue. 2015. "Detecting the association between meteorological factors and hand, foot, and mouth disease using spatial panel data models." International Journal of Infectious Diseases 34, no. : 66-70.
Hand, foot, and mouth disease (HFMD) is the most common communicable disease in China. Shandong Province is one of the most seriously affected areas. The distribution of HFMD had spatial heterogeneity and seasonal characteristic in this setting. The aim of this study was to explore the associations between climate and HFMD by a Bayesian approach from spatio-temporal interactions perspective. The HFMD data of Shandong Province during 2008–2012 were derived from the China National Disease Surveillance Reporting and Management System. And six climatic indicators were obtained from the Meteorological Bureau of Shandong Province. The global spatial autocorrelation statistic (Moran’s I) was used to detect the spatial autocorrelation of HFMD cases in each year. The optimal one among four Bayesian models was further adopted to estimate the relative risk of the occurrence of HFMD via Markov chain Monte Carlo. The annual average incidence rate of HFMD was 104.40 per 100,000 in Shandong Province. Positive spatial autocorrelation appeared at county level (Moran’s I ≥0.30, P < 0.001). The best fitting Spatio-temporal interactive model showed that annual average temperature, annual average pressure, annual average relative humidity, annual average wind speed and annual sunshine hours were significantly positive related to the occurrence of HFMD. The estimated relative risk of 36, 87, 91, 79, 65 out of 140 counties for 2008–2012 respectively were significantly more than 1. There were obvious spatio-temporal heterogeneity of HFMD in Shandong Province, and the climatic indicators were associated with the epidemic of HFMD. Bayesian approach should be recommended to capture the spatial-temporal pattern of HFMD.
Yunxia Liu; Xianjun Wang; ChunKun Pang; Zhongshang Yuan; Hongkai Li; Fuzhong Xue. Spatio-temporal analysis of the relationship between climate and hand, foot, and mouth disease in Shandong province, China, 2008–2012. BMC Infectious Diseases 2015, 15, 146 -146.
AMA StyleYunxia Liu, Xianjun Wang, ChunKun Pang, Zhongshang Yuan, Hongkai Li, Fuzhong Xue. Spatio-temporal analysis of the relationship between climate and hand, foot, and mouth disease in Shandong province, China, 2008–2012. BMC Infectious Diseases. 2015; 15 (1):146-146.
Chicago/Turabian StyleYunxia Liu; Xianjun Wang; ChunKun Pang; Zhongshang Yuan; Hongkai Li; Fuzhong Xue. 2015. "Spatio-temporal analysis of the relationship between climate and hand, foot, and mouth disease in Shandong province, China, 2008–2012." BMC Infectious Diseases 15, no. 1: 146-146.
Chinese herbal medicines have been used for a long time to treat osteoporosis. The evidence of their benefits and harms needs to be systematically reviewed. To assess the beneficial and harmful effects of Chinese herbal medicines as a general experimental intervention for treating primary osteoporosis by comparing herbal treatments with placebo, no intervention and conventional medicine. We searched the following electronic databases to January 2013: the Specialised Register of the Cochrane Complementary Medicine Field, CENTRAL, MEDLINE, EMBASE, LILACS, JICST-E, AMED, Chinese Biomedical Database and CINAHL. Randomised controlled trials of Chinese herbal medicines compared with placebo, no intervention or conventional medicine were included. Two authors extracted data and assessed risk of bias independently. Disagreement was resolved by discussion. One hundred and eight randomised trials involving 10,655 participants were included. Ninety-nine different Chinese herbal medicines were tested and compared with placebo (three trials), no intervention (five trials) or conventional medicine (61 trials), or Chinese herbal medicines plus western medicine were compared with western medicine (47 trials). The risk of bias across all studies was unclear for most domains primarily due to inadequate reporting of study design. Although we rated the risk of selective reporting for all studies as unclear, only a few studies contributed numerical data to the key outcomes.Seven trials reported fracture incidence, but they were small in sample size, suffered from various biases and tested different Chinese herbal medicines. These trials compared Kanggusong capsules versus placebo, Kanggusong granule versus Caltrate or ipriflavone plus Caltrate, Yigu capsule plus calcium versus placebo plus calcium, Xianlinggubao capsule plus Caltrate versus placebo plus Caltrate, Bushen Zhuanggu granules plus Caltrate versus placebo granules plus Caltrate, Kanggusong soup plus Caltrate versus Caltrate, Zhuangguqiangjin tablets and Shujinbogu tablets plus calcitonin ampoule versus calcitonin ampoule. The results were inconsistent.One trial showed that Bushenhuoxue therapy plus calcium carbonate tablets and alfacalcidol had a better effect on quality of life score (scale 0 to 100, higher is better) than calcium carbonate tablets and alfacalcidol (mean difference (MD) 5.30; 95% confidence interval (CI) 3.67 to 6.93).Compared with placebo in three separate trials, Chinese herbal medicines (Migu decoction, Bushen Yigu soft extract, Kanggusong capsules) showed a statistically significant increase in bone mineral density (BMD) (e.g. Kanggusong capsules, MD 0.06 g/cm(3); 95% CI 0.02 to 0.10). Compared with no intervention in five trials, only two showed that Chinese herbal medicines had a statistically significant effect on increase in BMD (e.g. Shigu yin, MD 0.08 g/cm(3); 95% CI 0.03 to 0.13). Compared with conventional medicine in 61 trials, 23 showed that Chinese herbal medicines had a statistically significant effect on increase in BMD. In 48 trials evaluating Chinese herbal medicines plus western medication against western medication, 26 showed better effects of the combination therapy on increase in BMD.No trial reported death or serious adverse events of Chinese herbal medicines, while some trials reported minor adverse effects such as nausea, diarrhoea, etc. Current findings suggest that the beneficial effect of Chinese herbal medicines in improving BMD is still uncertain and more rigorous studies are warranted.
Yunxia Liu; Jian Ping Liu; Yun Xia. Chinese herbal medicines for treating osteoporosis. Cochrane Database of Systematic Reviews 2014, CD005467 .
AMA StyleYunxia Liu, Jian Ping Liu, Yun Xia. Chinese herbal medicines for treating osteoporosis. Cochrane Database of Systematic Reviews. 2014; (3):CD005467.
Chicago/Turabian StyleYunxia Liu; Jian Ping Liu; Yun Xia. 2014. "Chinese herbal medicines for treating osteoporosis." Cochrane Database of Systematic Reviews , no. 3: CD005467.
Drug-resistant tuberculosis (DR-TB) is a major public health problem caused by various factors. It is essential to systematically investigate the epidemiological and, in particular, the ecological factors of DR-TB for its prevention and control. Studies of the ecological factors can provide information on etiology, and assist in the effective prevention and control of disease. So it is of great significance for public health to explore the ecological factors of DR-TB, which can provide guidance for formulating regional prevention and control strategies.
Yunxia Liu; Shiwen Jiang; Yanxun Liu; Rui Wang; Xiao Li; Zhongshang Yuan; Lixia Wang; Fuzhong Xue. Spatial epidemiology and spatial ecology study of worldwide drug-resistant tuberculosis. International Journal of Health Geographics 2011, 10, 50 -50.
AMA StyleYunxia Liu, Shiwen Jiang, Yanxun Liu, Rui Wang, Xiao Li, Zhongshang Yuan, Lixia Wang, Fuzhong Xue. Spatial epidemiology and spatial ecology study of worldwide drug-resistant tuberculosis. International Journal of Health Geographics. 2011; 10 (1):50-50.
Chicago/Turabian StyleYunxia Liu; Shiwen Jiang; Yanxun Liu; Rui Wang; Xiao Li; Zhongshang Yuan; Lixia Wang; Fuzhong Xue. 2011. "Spatial epidemiology and spatial ecology study of worldwide drug-resistant tuberculosis." International Journal of Health Geographics 10, no. 1: 50-50.
Traditional herbal therapies have been used for a long time to treat gastrointestinal disorders including irritable bowel syndrome, and their effectiveness from clinical research evidence needs to be systematically reviewed.
Jian Ping Liu; Min Yang; Yunxia Liu; Mao Ling Wei; Sameline Grimsgaard. Herbal medicines for treatment of irritable bowel syndrome. Cochrane Database of Systematic Reviews 2006, 1 .
AMA StyleJian Ping Liu, Min Yang, Yunxia Liu, Mao Ling Wei, Sameline Grimsgaard. Herbal medicines for treatment of irritable bowel syndrome. Cochrane Database of Systematic Reviews. 2006; (1):1.
Chicago/Turabian StyleJian Ping Liu; Min Yang; Yunxia Liu; Mao Ling Wei; Sameline Grimsgaard. 2006. "Herbal medicines for treatment of irritable bowel syndrome." Cochrane Database of Systematic Reviews , no. 1: 1.
Yunxia Liu; Jianping Liu. Herbal medicines for treating osteoporosis. Cochrane Database of Systematic Reviews 2005, 1 .
AMA StyleYunxia Liu, Jianping Liu. Herbal medicines for treating osteoporosis. Cochrane Database of Systematic Reviews. 2005; ():1.
Chicago/Turabian StyleYunxia Liu; Jianping Liu. 2005. "Herbal medicines for treating osteoporosis." Cochrane Database of Systematic Reviews , no. : 1.
Yun-Xia Liu; Jie-Zhen Wang; Jian-Ping Liu; Chun-Kun Pang; Hong-Ying Jia. [Imaging diagnosis for fatty liver: a systematic review]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2004, 26, 1 .
AMA StyleYun-Xia Liu, Jie-Zhen Wang, Jian-Ping Liu, Chun-Kun Pang, Hong-Ying Jia. [Imaging diagnosis for fatty liver: a systematic review]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2004; 26 (5):1.
Chicago/Turabian StyleYun-Xia Liu; Jie-Zhen Wang; Jian-Ping Liu; Chun-Kun Pang; Hong-Ying Jia. 2004. "[Imaging diagnosis for fatty liver: a systematic review]." Zhongguo Yi Xue Ke Xue Yuan Xue Bao 26, no. 5: 1.
Yunxia Liu; ChunKun Pang; Jian Ping Liu. Medicinal herbs for acute hepatitis B. Cochrane Database of Systematic Reviews 2004, 1 .
AMA StyleYunxia Liu, ChunKun Pang, Jian Ping Liu. Medicinal herbs for acute hepatitis B. Cochrane Database of Systematic Reviews. 2004; ():1.
Chicago/Turabian StyleYunxia Liu; ChunKun Pang; Jian Ping Liu. 2004. "Medicinal herbs for acute hepatitis B." Cochrane Database of Systematic Reviews , no. : 1.
Yun-Xia Liu; Jie-Zhen Wang. [Meta-analysis of the relationship between smoking and stomach cancer]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao 2002, 24, 1 .
AMA StyleYun-Xia Liu, Jie-Zhen Wang. [Meta-analysis of the relationship between smoking and stomach cancer]. Zhongguo Yi Xue Ke Xue Yuan Xue Bao. 2002; 24 (6):1.
Chicago/Turabian StyleYun-Xia Liu; Jie-Zhen Wang. 2002. "[Meta-analysis of the relationship between smoking and stomach cancer]." Zhongguo Yi Xue Ke Xue Yuan Xue Bao 24, no. 6: 1.