With the growing availability and popularity of sentiment-rich resources like blogs and online reviews, new opportunities and challenges have emerged regarding the identification, extraction, and organization of sentiments from user-generated documents or sentences. Recently, many studies have exploited lexicon-based methods or supervised learning algorithms to separately conduct sentiment analysis tasks; however, the former approaches ignore contextual information of sentences and the latter ones do not take sentiment information embedded in sentiment words into consideration. To tackle these limitations, we propose a new model named Sentiment Convolutional Neural Network (SentiCNN) to analyze the sentiments of sentences with both contextual and sentiment information of sentiment words, in which, contextual information is captured from word embeddings and sentiment information is identified using existing lexicons. We incorporate a Highway Network into our model to adaptively combine sentiment and contextual information from sentences by strengthening the connection between features of both sentences and their sentiment words. Furthermore, we propose three lexicon-based attention mechanisms (LBAMs) for our SentiCNN model to find the most important indicators of sentiments and make predictions more effectively. Experiments over two well-known datasets indicate that sentiment words, the Highway Network, and LBAMs contribute to sentiment analysis.

Natural language processing (NLP) is an effective tool for generating structured information from unstructured data, the one that is commonly found in clinical trial texts. Such interdisciplinary research has gradually grown into a flourishing research field with accumulated scientific outputs available. In this study, bibliographical data collected from Web of Science, PubMed, and Scopus databases from 2001 to 2018 had been investigated with the use of three prominent methods, including performance analysis, science mapping, and, particularly, an automatic text analysis approach named structural topic modeling. Topical trend visualization and test analysis were further employed to quantify the effects of the year of publication on topic proportions. Topical diverse distributions across prolific countries/regions and institutions were also visualized and compared. In addition, scientific collaborations between countries/regions, institutions, and authors were also explored using social network analysis. The findings obtained were essential for facilitating the development of the NLP-enhanced clinical trial texts processing, boosting scientific and technological NLP-enhanced clinical trial research, and facilitating inter-country/region and inter-institution collaborations.