The article presents a model of a near-field sensor for non-invasive glucose monitoring. The sensor has a specific design and forms a rather extended near-field. Due to this, the high penetration of electromagnetic waves into highly absorbing media (biologic media) is achieved. It represents a combined slot antenna based on a flexible RO3003 substrate. Moreover, it is small and rather flat (25 mm in diameter, 0.76 mm thick). These circumstances are the distinguishing features of this sensor in comparison with microwave sensors of other designs. The article presents the results of numerical modeling and experimental verification of a near-field sensor. Furthermore, a phantom of human biological media (human hand) was created for experimentation. In the case of numerical modeling, the sensor is located close to the hand model. In a full-scale experiment, it is located close to the phantom of the human hand for the maximum interaction of the near-field with biological materials. As a result of a series of measurements for this sensor, the reflection coefficient is measured, and the dependences of the reflected signal on the frequency are plotted. According to the results of the experiments carried out, there is a clear difference in glucose concentrations. At the same time, the accuracy of determining the difference in glucose concentrations is high. The values of the amplitude of the reflected signal with a change in concentration differ by 0.5–0.8 dB. This sensor can be used for developing a non-invasive blood glucose measurement procedure.
The paper presents results of numerical simulation and experimental testing of a microwave sensor for non-invasive glucose monitoring. The sensor represents a conical horn with a conical conductor inside expanding toward the horn aperture. Such a sensor has a significantly wider passband in comparison with sensors of other designs. It is essential that the sensor geometry provides formation of an extended near-field zone with high electric field strength near the sensor aperture. A clear relationship between the dielectric permittivity of the phantom biological tissue and the frequency dependence of the parameter S11 of the sensor is observed at frequencies in the range from 1.4 to 1.7 GHz. This circumstance can be used to develop a procedure for measuring the glucose level in blood that correlates with the parameter S11 of the sensor. From the viewpoint of monitoring of the glucose content in blood, the most convenient body sensor location is on the hands or feet, in particular, wrists.
The article is about the development of a new non-destructive microwave method for measuring the electrophysical properties of materials, based on the method of transmission and reflection of a plane monochromatic wave through layered materials. The method has been verified by the results of numerical and field experiments. A data processing technique is described for obtaining complex values of dielectric and magnetic permeability based on an original measurement scheme. Based on the results of mathematical calculations, the laboratory model was created using an ultra-wideband antenna and a parabolic mirror. The optimal distance of the antenna from the parabolic mirror for focusing the electromagnetic field has been determined based on the simulation. Testing was carried out in the frequency range 3–13 GHz on two samples of materials (plexiglass and textolite) with known electrophysical properties. The obtained results showed the reliability of the developed method and its applicability. The measurement error was less than 2%.
The article presents the design of the near-field probe, which is a combined emitter (a combination of a symmetric dipole and an annular frame). The design of the probe allows forming a prolonged zone of the near-field. This effect can be used for in-depth penetration of the field in media with high absorption, without loss of information. Particular attention in this article is given to a detailed study of the interaction of the field created by this probe on plane-layered biological media. A theoretical analysis of the interaction of the electromagnetic field was carried out in a wide frequency band with a model plane-layer biological medium containing blood vessels of shallow depth using the proposed probe design. Conclusions are drawn about the depth of penetration of a useful signal into different media-analogs of biological tissue. This study is necessary to consider the possibility of using this probe for non-invasive measurements of blood glucose concentration. The studies were carried out using numerical simulation in the CST (Computer Simulation Technology) Microwave Studio environment. All biological tissues were simulated over a wide frequency range from 10 MHz to 10 GHz.
This article demonstrates a model of a near-field sensor, which is a combined slot antenna based on a flexible substrate RO3003. It is shown that the sensor has a high penetration of electromagnetic waves into highly absorbing media due to the length of the near field. In addition, it has a small size (diameter the sensor is 25 mm, thickness 0.76 mm). The simplified model of a hand simplified with a shallow vein depth was constructed. This model based on the experimentally obtained data of dielectric constant for glucose concentrations of 1.2–10 mmol/l. The simulation results, carried out in the frequency range 0.5–5 GHz, showed the possibility of determining a small change in blood sugar level from the reflected signal data.
A method for solving the inverse problem for reconstructing the spatial distribution of dielectric permittivity from the results of multi-angle transmission broadband radiosounding is proposed. The method is based on inverse wave propagation. The average refractive index of the medium along the wave trajectory is calculated by comparing the results of the calculation of the time delay of the inverse signal in the entire sounding region and the forward propagation time in a homogeneous medium. This method takes into account diffraction effects in solving a direct problem, which allows one to obtain a resolution in the order of a wavelength. The combination of time delays obtained at different probing angles allows the restoration of the distribution of the refractive index in the medium. The paper presents the results of the numerical simulation of this method. The novelty of the proposed approach compared to the conventional back-projection algorithm is that ray approximation is not applied. Instead of the absorption coefficient (used in X-ray tomography), a time delay is considered, which is restored in the entire probed region. The developed method can be widely used in radiowave tomography or microwave tomography for remote non-destructive testing, diagnostics for the internal structures of inhomogeneous media and the restoration of the shapes of opaque objects based on multisensor sensing.