Khakhanang Ratananikom

Dr. Khakhanang Ratananikom


Research Focus & Metrics

Academic Career Length

17Years (2010-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

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23 December 2010 in Angewandte Chemie International Edition
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DKDavid H. Kwan
David H. Kwan
HCHong‐Ming Chen
Hong‐Ming Chen
KRKhakhanang Ratananikom
Khakhanang Ratananikom
SHSusan M. Hancock
Susan M. Hancock
YWYoichiro Watanabe
Yoichiro Watanabe
SWStephen Withers
Stephen Withers

3 April 2022 in Nanomaterials
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YMYumatorn Mingmongkol
Yumatorn Mingmongkol
DTDang T.T. Trinh
Dang T.T. Trinh
PPPatcharaporn Phuinthiang
Patcharaporn Phuinthiang
DCDuangdao Channei
Duangdao Channei
KRKhakhanang Ratananikom
Khakhanang Ratananikom
WKWilawan Khanitchaidecha
Wilawan Khanitchaidecha
In this work, metal-doped titanium dioxide (TiO2) was synthesised with the aim of improving photocatalytic degradation and antimicrobial activities; TiO2 was doped with copper (Cu) ranging from 0.1 to 1.0 wt%. The physical and chemical properties of the Cu-doped TiO2 nanoparticles were characterized by X-ray diffraction (XRD), transmission electron microscopy (TEM), the Brunauer–Emmett–Teller method (BET) and diffuse reflection spectroscopy (DRS). The results revealed that the anatase phase of TiO2 was maintained well in all the Cu-doped TiO2 samples. No significant difference in the particle sizes or the specific surface areas was caused by increasing Cu doping. However, the band gap decreased continuously from 3.20 eV for undoped TiO2 to 3.12 eV for 1.0 wt.% Cu-doped TiO2. In addition, the 0.1 wt.% Cu-doped TiO2 displayed a much greater photocatalytic degradation of methylene blue (MB) and excellent antibacterial ability for Escherichia coli (E. coli) compared to undoped TiO2. On the other hand, the high Cu doping levels had negative impacts on the surface charge of nanoparticles and charge transfer for OH• generation, resulting in decreasing MB degradation and E. coli photokilling for 1.0 wt.% Cu-doped TiO2.

2 December 2022 in Scientifica
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KRKhakhanang Ratananikom
Khakhanang Ratananikom
KPKantapon Premprayoon
Kantapon Premprayoon
This study evaluated the effect of ultrasonic-assisted extraction (UAE) on the isolation of phenolic compounds, flavonoids, and antioxidants from dill. UAE improved the extraction yields of total phenolic compounds and total flavonoid content as well as increased the antioxidant activities of all dill extracts. The optimum UAE condition to obtain highest total phenolic compounds, total flavonoid content, and antioxidant activities was 50 ethanol for 30min giving 135.883.23mg gallic acid equivalent/g extract and 229.534.97mg rutin equivalent/g extract, respectively. Lowest IC50 values against 2,2-azino-bis (3-ethylbenzothiazoline-6-sulfonic acid) (ABTS) and 2,2-diphenyl-1-picrylhydrazyl (DPPH) radicals were 0.0340.00mg/mL and 0.120.00mg/mL, respectively. Results indicated the capability of UAE in extracting biologically active compounds from dill as a prospective functional material.

4 June 2021 in Nanomaterials
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PPPatcharaporn Phuinthiang
Patcharaporn Phuinthiang
DTDang T.T. Trinh
Dang T.T. Trinh
DCDuangdao Channei
Duangdao Channei
KRKhakhanang Ratananikom
Khakhanang Ratananikom
SSSirikasem Sirilak
Sirikasem Sirilak
ANAuppatham Nakaruk
Auppatham Nakaruk
This work demonstrates a novel method to deposit an antibacterial TiO2 thin film on a polymer substrate at room temperature. A combination of sol–gel and photon assistance was used in the experiment in order to avoid any thermal processes of thin film crystallization. The morphological photograph of samples indicated that the TiO2 thin film was perfectly coated on the PVC substrate without any cracks or pinholes. Chemical analysis by EDS and XPS reported that the thin film consisted of titanium (Ti), oxygen (O), and carbon (C). The Raman spectrum proved that the thin film was the anatase phase of TiO2 and, furthermore, that it was contaminated with carbon remaining from the photon assistance process. In addition, the optical band gap of the thin film was 3.35 eV, suggesting that the photocatalytic activity of TiO2 should occur under UV-A radiation. The bacteria viability assay was examined using E. coli and S. typhimurium as indicator strains under UV-A irradiation (365 nm) at different times. The data from OD and CFU count revealed that >97% of bacteria were killed after 60 min of irradiation, and the bacteria were completely killed at 120 min for E. coli and 180 min for S. typhimurium.

1 December 2010 in Journal of Molecular Catalysis B: Enzymatic
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PKPrachumporn T. Kongsaeree
Prachumporn T. Kongsaeree
KRKhakhanang Ratananikom
Khakhanang Ratananikom
KCKhuanjarat Choengpanya
Khuanjarat Choengpanya
NTNusra Tongtubtim
Nusra Tongtubtim
PSPenporn Sujiwattanarat
Penporn Sujiwattanarat
JSJisnuson Svasti
Jisnuson Svasti

1 January 2024 in Scientifica
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Journal Article
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KRKhakhanang Ratananikom
Khakhanang Ratananikom
VJVichayut Juntaree
Vichayut Juntaree
WWWoragon Wichaiyo
Woragon Wichaiyo
KKKris Khunluek
Kris Khunluek
KPKantapon Premprayoon
Kantapon Premprayoon
JKJittawan Kubola
Jittawan Kubola
Diabetes management through dietary intervention has gained significant interest, particularly in the use of natural plant‐based inhibitors of key enzymes involved in carbohydrate digestion. The objective of this study was to assess the inhibitory effects of ten Thai culinary vegetables on α‐glucosidase and α‐amylase, including Chinese chive (Allium tuberosum), holy basil (Ocimum tenuiflorum), star gooseberry (Phyllanthus acidus), galangal (Alpinia galanga), bamboo grass (Tiliacora triandra), Turkey berry (Solanum torvum), cassod tree (Senna siamea), dill (Anethum graveolens L.), noni (Morinda citrifolia), and pearl wattle (Leucaena leucocephala). All vegetables were extracted using deionized water at a 1 : 10 ratio in an ultrasonic bath operating at 350 W and a frequency of 50 Hz for 30 minutes. The α‐glucosidase inhibitory activities of the vegetable extracts ranged from 13.42 ± 0.23% to 79.84 ± 0.47%, while the inhibitory activities against α‐amylase were relatively modest, ranging from 4.82 ± 3.32% to 27.49 ± 1.67%. Cassod tree exhibited the highest α‐glucosidase inhibition with the lowest IC50 at 126.38 ± 0.98 μg/mL, followed by galangal (203.17 ± 1.05 μg/mL) and holy basil (1,240 ± 20.31 μg/mL), respectively. These results may hold promise for encouraging the consumption of vegetables as a strategy for diabetes management through the targeting of key enzyme inhibition.