Parkinson’s Disease (PD) is a progressive central nervous system disorder that is caused due to the neural degeneration mainly in the substantia nigra in the brain. It is responsible for the decline of various motor functions due to the loss of dopamine-producing neurons. Tremors in hands is usually the initial symptom, followed by rigidity, bradykinesia, postural instability, and impaired balance. Proper diagnosis and preventive treatment can help patients improve their quality of life. We have proposed an ensemble of Deep Learning (DL) models to predict Parkinson’s using DaTscan images. Initially, we have used four DL models, namely, VGG16, ResNet50, Inception-V3, and Xception, to classify Parkinson’s disease. In the next stage, we have applied a Fuzzy Fusion logic-based ensemble approach to enhance the overall result of the classification model. The proposed model is assessed on a publicly available database provided by the Parkinson’s Progression Markers Initiative (PPMI). The achieved recognition accuracy, Precision, Sensitivity, Specificity, F1-score from the proposed model are 98.45%, 98.84%, 98.84%, 97.67%, and 98.84%, respectively which are higher than the individual model. We have also developed a Graphical User Interface (GUI)-based software tool for public use that instantly detects all classes using Magnetic Resonance Imaging (MRI) with reasonable accuracy. The proposed method offers better performance compared to other state-of-the-art methods in detecting PD. The developed GUI-based software tool can play a significant role in detecting the disease in real-time.

Nowadays, researchers aim to enhance man-to-machine interactions by making advancements in several domains. Facial emotion recognition (FER) is one such domain in which researchers have made significant progresses. Features for FER can be extracted using several popular methods. However, there may be some redundant/irrelevant features in feature sets. In order to remove those redundant/irrelevant features that do not have any significant impact on classification process, we propose a feature selection (FS) technique called the supervised filter harmony search algorithm (SFHSA) based on cosine similarity and minimal-redundancy maximal-relevance (mRMR). Cosine similarity aims to remove similar features from feature vectors, whereas mRMR was used to determine the feasibility of the optimal feature subsets using Pearson’s correlation coefficient (PCC), which favors the features that have lower correlation values with other features—as well as higher correlation values with the facial expression classes. The algorithm was evaluated on two benchmark FER datasets, namely the Radboud faces database (RaFD) and the Japanese female facial expression (JAFFE). Five different state-of-the-art feature descriptors including uniform local binary pattern (uLBP), horizontal–vertical neighborhood local binary pattern (hvnLBP), Gabor filters, histogram of oriented gradients (HOG) and pyramidal HOG (PHOG) were considered for FS. Obtained results signify that our technique effectively optimized the feature vectors and made notable improvements in overall classification accuracy.

The novel SARS-CoV-2 virus, responsible for the dangerous pneumonia-type disease, COVID-19, has undoubtedly changed the world by killing at least 3,900,000 people as of June 2021 and compromising the health of millions across the globe. Though the vaccination process has started, in developing countries such as India, the process has not been fully developed. Thereby, a diagnosis of COVID-19 can restrict its spreading and level the pestilence curve. As the quickest indicative choice, a computerized identification framework ought to be carried out to hinder COVID-19 from spreading more. Meanwhile, Computed Tomography (CT) imaging reveals that the attributes of these images for COVID-19 infected patients vary from healthy patients with or without other respiratory diseases, such as pneumonia. This study aims to establish an effective COVID-19 prediction model through chest CT images using efficient transfer learning (TL) models. Initially, we used three standard deep learning (DL) models, namely, VGG-16, ResNet50, and Xception, for the prediction of COVID-19. After that, we proposed a mechanism to combine the above-mentioned pre-trained models for the overall improvement of the prediction capability of the system. The proposed model provides 98.79% classification accuracy and a high $F_1$-score of 0.99 on the publicly available SARS-CoV-2 CT dataset. The model proposed in this study is effective for the accurate screening of COVID-19 CT scans and, hence, can be a promising supplementary diagnostic tool for the forefront clinical specialists.