Hefei National Lab for Physical Sciences at the Microscale and the Centers for Biomedical Engineering, University of Science and Technology of China, Hefei 230027, China
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Dr. Muhammad Imran Khan
Hefei National Lab for Physical Sciences at the Microscale and the Centers for Biomedical Engineering, University of Science and Technology of China, Hefei 230027, China
Misuse of antibiotics has recently been considered a global issue because of its harmful effects on human health. Since conventional methods have numerous limitations, it is necessary to develop fast, simple, sensitive, and reproducible methods for the detection of antibiotics. Among numerous recently developed methods, aptasensors are fascinating because of their good specificity, sensitivity and selectivity. These kinds of biosensors combining aptamer with colorimetric applications of gold nanoparticles to recognize small molecules are becoming more popular owing to their advantageous features, for example, low cost, ease of use, on-site analysis ability using naked eye and no prerequisite for modern equipment. In this review, we have highlighted the recent advances and working principle of gold nanoparticles based colorimetric aptasensors as promising methods for antibiotics detection in different food and environmental samples (2011–2020). Furthermore, possible advantages and disadvantages have also been summarized for these methods. Finally, the recent challenges, outlook, and promising future perspectives for developing novel aptasensors are also considered.
1 June 2021 in International Journal of Biological Macromolecules
In this article, a novel maximum power point tracking (MPPT) controller for the fast-changing irradiance of photovoltaic (PV) systems is introduced. Our technique utilizes a modified incremental conductance (IC) algorithm for the efficient and fast tracking of MPP. The proposed system has a simple implementation, fast tracking, and achieved steady-state oscillation. Traditional MPPT techniques use a tradeoff between steady-state and transition-state parameters. The shortfalls of various techniques are studied. A comprehensive comparative study is done to test various existing techniques against the proposed technique. The common parameters discussed in this study are fast convergence, efficiency, and reduced oscillations. The proposed method successfully addresses these issues and improves the results significantly by using a proportional integral deferential (PID) controller with a genetic algorithm (GA) to predict the variable step size of the IC-based MPPT technique. The system is designed and tested against the perturbation and observation (P&O)-based MPPT technique. Our technique effectively detects global maxima (GM) for fast-changing irradiance due to the adopted GA-based tuning of the controller. A comparative analysis of the results proves the superior performance and capabilities to track GM in fewer iterations.
The most cost-effective electrical energy is produced by photovoltaic (PV) systems, and with the smallest carbon footprint, making it a sustainable renewable energy. They provide an excellent alternative to the existing fossil fuel-based energy systems, while providing 4% of global electricity demand. PV system efficiency is significantly reduced by the intrinsic non-linear model, maximum power point (MPP), and partial shading (PS) effects. These two problems cause major power loss. To devise the maximum power point tracking (MPPT) control of the PV system, a novel group teaching optimization algorithm (GTOA) based controller is presented, which effectively deals with the PS and complex partial shading (CPS) conditions. Four case studies were employed that included fast-changing irradiance, PS, and CPS to test the robustness of the proposed MPPT technique. The performance of the GTOA was compared with the latest bio-inspired techniques, i.e., dragon fly optimization (DFO), cuckoo search (CS), particle swarm optimization (PSO), particle swarm optimization gravitational search (PSOGS), and conventional perturb and observe (P&O). The GTOA tracked global MPP with the highest 99.9% efficiency, while maintaining the magnitude of the oscillation <0.5 W at global maxima (GM). Moreover, 13–35% faster tracking times, and 54% settling times were achieved, compared to existing techniques. Statistical analysis was carried out to validate the robustness and effectiveness of the GTOA. Comprehensive analytical and statistical analysis solidified the superior performance of the proposed GTOA based MPPT technique.