The evolution toward electric vehicle nowadays appears to be the main stream in the automotive and transportation industry. In this paper, our attention is focused on the architectural modifications that should be introduced into the car body to give a proper location to the battery pack. The required battery pack is a big, heavy, and expensive component to be located, managed, climatized, maintained, and protected. This paper develops some engineering analyses and shows sketches of some possible solutions that could be adopted. The possible consequences on the position of the vehicle center of gravity, which in turn could affect the vehicle drivability, lead to locate the battery housing below the passenger compartment floor. This solution is also one of the most interesting from the point of view of the battery pack protection in case of a lateral impact and for easy serviceability and maintenance. The integration of the battery pack’s housing structure and the vehicle floor leads to a sort of sandwich structure that could have beneficial effects on the body’s stiffness (both torsional and bending). This paper also proposes some considerations that are related to the impact protection of the battery pack, with particular reference to the side impacts against a fixed obstacle, such as a pole, which are demonstrated to be the most critical. By means of some FE simulation results, the relevance of the interplay among the different parts of the vehicle side structure and battery case structure is pointed out.