Coccidiosis is the most prevalent disease causing widespread economic loss, especially in poultry farms. Here, we investigated the effects of pomegranate peel extract (PPE) on the outcome of coccidiosis caused byEimeria papillatain mice. The data showed that mice infected withE. papillataand treated with PPE revealed a significant decrease in the output of oocysts in their faeces by day 5 p.i. Infection also induced inflammation and injury of the jejunum. This was evidenced (i) as increases in reactive oxygen species, (ii), as increased neutrophils and decreased lymphocytes in blood (ii) as increased mRNA levels of inducible nitric oxide synthase (iNOS), Bcl-2 gene, and of the cytokines interferon gamma (IFN-γ), tumour necrosis factor-α(TNF-α), and interleukin-1β(IL-1β), and (iv) as downregulation of mucin gene MUC2 mRNA. All these infection-induced parameters were significantly altered during PPE treatment. In particular, PPE counteracted theE. papillata-induced loss of the total antioxidant capacity. Our data indicated that PPE treatment significantly attenuated inflammation and injury of the jejunum induced byE. papillatainfections.

This study is a retrospective analysis of the recorded intestinal parasitic infections for in- and outpatients visiting King Fahd Medical City, Riyadh, Saudi Arabia, from 2013 to 2017. In this study, a total of 5987 in- and outpatient were examined for intestinal parasitic infection. 30 patients out of 5987 were infected with 6 species of intestinal parasites with prevalence rate 0.5%. These parasites wereEntamoeba histolytica(P = 0.27%),Cryptosporidiumsp. (P = 0.1%),Giardia lamblia(P = 0.07%),Trichuris trichiura(P = 0.03%),Hymenolepis nana(P = 0.02%), andChilomastix mesnili(P = 0.02%). The prevalence of infection in both males and females was 0.38% and 0.58%, respectively. Also, the prevalence of infection in different years and age groups as well as different seasons was provided. Intestinal parasitic infections are still a public health problem in Riyadh region, Saudi Arabia. Updating the epidemiologic survey of these parasites at regular intervals using the appropriate statistical methods is necessary to develop effective prevention and control strategies.

Introduction: Saudi Arabia has successfully reduced malaria cases to be constrained largely in the western regions. This study aimed to determine the epidemiological trends of malaria infection in five western regions of Saudi Arabia. Methodology: A retrospective analysis was conducted to investigate the epidemiological trends of malaria infection in the western regions, based on the published registry of the Saudi Ministry of Health, during the period from 2014 to 2017 using the appropriate statistical tools. Results: A total of 8925 confirmed cases of malaria were reported in the western regions during the period from 2014 to 2017 with the mean of 2231 malaria cases per year. The minimum (n = 1097) and maximum (n = 4075) number of cases were reported in 2014 and 2016 respectively. The highest (n = 5919, 66.3%) number of cases were reported from Jazan region, while lowest (n = 86, 1.0%) number of cases were reported from Al-Bahah region. Plasmodium falciparum was the most frequently reported species with 7485 (83.9%) cases, while Plasmodium vivax accounted 1386 (15.5%) cases. Plasmodium malariae and mixed infections were insignificant and accounted 0.5% (n = 48) and 0.1% (n = 6) cases respectively. In relation to malaria infection and age group, malaria was predominant in > 15 age group. The highest number of malaria cases in almost all years was observed from January until March and the lowest number was reported from May until July. Conclusions: Plasmodium falciparum was the most dominant species in this survey and Jazan was the most affected region.

This is a retrospective analysis of reported intestinal parasitic infections for patients visiting Prince Sultan Military Medical City, Riyadh, KSA from 2010 to 2014. Our retrospective study estimated a total 775 case out of 11110 case were infected with one or more intestinal parasites, with prevalence rate 6.98 %. The prevalence of intestinal parasitic infection during the period of study was as follows; Ascaris lumbricoides (n= 205, 1.8%), Giardia lamblia (n= 178, 1.6%), Entamoeba histolytica (n= 174, 1.57%), Trichuris trichiura (n= 118, 1.06%), Hymenolepis nana (n= 51, 0.46 %), Enterobius vermicularis (n= 28, 0.25%) and Taenia saginata (n= 21, 0.19%) respectively. The prevalence rate of these parasites in males and females as well as different age groups per month / year is provided. Intestinal parasitic infection is still a public health problem in Riyadh region, KSA. It is necessary to update the epidemiologic survey of the parasitic infection at regular intervals using different statistical methods to develop effective prevention and control strategies.

One of the most important problems faced by world at the present time is food deficiency. Today the third world is facing protein deficiency as one of the major global challenges. In Egypt, the continuous population explosion requires more food production to meet the consequent increasing demands. However, there are many zoonotic fish parasites not only in Egypt but worldwide.