Frank Ruhli

Dr. Frank Ruhli

orcid

Research Focus & Metrics

Academic Career Length

14Years (2013-Present)

(Calculated once Scilit publication data is synced: current year − year of first publication + 1)

Representative Publications

View All Publications
3 March 2016 in Clinical Anatomy
Verified
Journal Article
Closed access
PDF file
FRFrank Ruhli
Frank Ruhli
FGFrancesco M. Galassi
Francesco M. Galassi
MHMartin Haeusler
Martin Haeusler

10 January 2017 in BMC Musculoskeletal Disorders
Verified
Journal Article
Open access
PDF file
SMSandra Mathews
Sandra Mathews
Marco D. BurkhardMarco D. Burkhard
Marco D. Burkhard
NSNabil Serrano
Nabil Serrano
KLKarl Link
Karl Link
MHMartin Haeusler
Martin Haeusler
EEElisabeth Eppler
Elisabeth Eppler
Placement of the glenoid baseplate is of paramount importance for the outcome of anatomical and reverse total shoulder arthroplasty. However, the database around glenoid size is poor, particularly regarding small scapulae, for example, in women and smaller individuals, and is derived from different methodological approaches. In this multimodality cadaver study, we systematically examined the glenoid using morphological and 3D-CT measurements. Measurements of the glenoid and drill hole tunnel length for superior baseplate screw placement were recorded to define size of the glenoid and the distance to the scapular notch on cadaveric specimens. Glenoid angles were determined on both, 3D-CT-scans of the thoraxes using the Friedman method and on subsequently isolated scapulae from 18 male and female donors (average 84 years, range 60–98 years). Mean glenoid height was 36.6 mm ± 3.6, and width 27.8 mm ± 3.1 with a significant sex dimorphism (p ≤ 0.001): in males, glenoid height 39.5 mm ± 3.5, and width 30.3 mm ± 3.3, and in females, glenoid height 34.8 mm ± 2.2, and width 26.2 mm ± 1.6. The average distance from the superior screw entry to its exit in the scapular notch measured by calliper was 27.2 mm ± 6.0 with a sex difference: in males, 29.4 mm ± 5.7, and in females, 25.8 mm ± 5.9 mm with a minimum recorded distance of 15 mm. Measured by CT, the mean inclination angle for male and female donors combined was 13.0° ± 7.0, and the ante-/retroversion angle −1.0° ± 4.0°. This study is one of the first to combine dissection, including drill holes, with anatomical measurements and radiological data. In some women and smaller individuals, smaller baseplates should be selected. The published safe zone of 20 mm is generally feasible for superior screw placement, however, in small patients this distance may be substantially shorter than expected and start as of 13 and 15 mm, respectively. No correlation between glenoid height or width with the length of our drilling canal towards the scapular notch was found. Preoperative CT-based treatment planning to determine version and inclination angles is recommended.

27 April 2015 in American Journal of Physical Anthropology
Verified
Journal Article
Closed access
MHMichael E. Habicht
Michael E. Habicht
MHMaciej Henneberg
Maciej Henneberg
LÖLena M. Öhrström
Lena M. Öhrström
KSKaspar Staub
Kaspar Staub
FRFrank Ruhli
Frank Ruhli

26 September 2018 in BMC Cancer
Verified
Journal Article
Open access
PDF file
Wenpeng YouWenpeng You
Wenpeng You
FRFrank Ruhli
Frank Ruhli
RHRenata J Henneberg
Renata J Henneberg
MHMaciej Henneberg
Maciej Henneberg
Greater family size measured with total fertility rate (TFR) and with household size, may offer more life satisfaction to the family members. Positive psychological well-being has been postulated to decrease cancer initiation risk. This ecological study aims to examine the worldwide correlation between family size, used as the measure of positive psychological well-being, and total cancer incidence rates. Country specific estimates obtained from United Nations agencies on total cancer incidence rates (total, female and male rates in age range 0–49 years and all ages respectively), all ages site cancer incidence (bladder, breast, cervix uteri, colorectum, corpus uteri, lung, ovary and stomach), TFR, household size, life expectancy, urbanization, per capita GDP PPP and self-calculated Biological State Index (Ibs) were matched for data analysis. Pearson’s, non-parametric Spearman’s, partial correlations, independent T-test and multivariate regressions were conducted in SPSS. Worldwide, TFR and household size were significantly and negatively correlated to all the cancer incidence variables. These correlations remained significant in partial correlation analysis when GDP, life expectancy, Ibs and urbanization were controlled for. TFR correlated to male cancer incidence rate (all ages) significantly stronger than it did to female cancer incidence rate (all ages) in both Pearson’s and partial correlations. Multivariate stepwise regression analysis indicated that TFR and household size were consistently significant predictors of all cancer incidence variables. Countries with greater family size have lower cancer risk in both females, and especially males. Our results seem to suggest that it may be worthwhile further examining correlations between family size and cancer risk in males and females through the cohort and case-control studies based on large samples.

22 May 2015 in The Anatomical Record
Verified
Journal Article
Open access
PDF file
BLBettina M. Kreissl Lonfat
Bettina M. Kreissl Lonfat
IKIna Maria Kaufmann
Ina Maria Kaufmann
FRFrank Ruhli
Frank Ruhli
As clinical research constantly advances and the concept of evolution becomes a strong and influential part of basic medical research, the absence of a discourse that deals with the use of ancient human remains in evidence‐based research is becoming unbearable. While topics such as exhibition and excavation of human remains are established ethical fields of discourse, when faced with instrumentalization of ancient human remains for research (i.e., ancient DNA extractions for disease marker analyses) the answers from traditional ethics or even more practical fields of bio‐ethics or more specific biomedical ethics are rare to non‐existent. The Centre for Evolutionary Medicine at the University of Zurich solved their needs for discursive action through the writing of a self‐given code of ethics which was written in dialogue with the researchers at the Institute and was published online in Sept. 2011: http://evolutionäremedizin.ch/coe/. The philosophico‐ethical basis for this a code of conduct and ethics and the methods are published in this article. Anat Rec, 298:1175–1181, 2015.

22 May 2015 in The Anatomical Record
Verified
Journal Article
Open access
PDF file
LÖLena Öhrström
Lena Öhrström
BFBernd M. Fischer
Bernd M. Fischer
ABAndreas Bitzer
Andreas Bitzer
JWJan Wallauer
Jan Wallauer
MWMarkus Walther
Markus Walther
FRFrank Ruhli
Frank Ruhli
During the last few years, terahertz (THz) imaging has been used to investigate artwork and historic artifacts. The application of THz imaging to mummy investigations is very attractive since it provides spectroscopic information over a broad frequency range and its radiation has proven to be harmless to human cells. However, compared with the current standard imaging methods in mummy imaging—X‐ray and computed tomography (CT)—it remains a novel, emerging technique whose potential still needs to be fully evaluated. Here, ancient Egyptian mummified objects as well as a naturally mummified rat have been investigated by two different THz imaging systems: a broadband THz time domain imaging system and an electronic THz scanner. The obtained THz images are compared with conventional CT, X‐ray, and magnetic resonance images. While the broadband THz time domain setup permits analyses of smaller samples, the electronic THz scanner allows the recording of data of thicker and larger samples at the expense of a limited spectral bandwidth. Terahertz imaging shows clear potential for mummy investigations, although currently CT imaging offers much higher spatial resolution. Furthermore, as commercial mobile THz scanners become available, THz imaging could be applied directly in museums or at excavation sites. Anat Rec, 298:1135–1143, 2015.