In statistical analyses, especially those using a multiresponse regression model approach, a mathematical model that describes a functional relationship between more than one response variables and one or more predictor variables is often involved. The relationship between these variables is expressed by a regression function. In the multiresponse nonparametric regression (MNR) model that is part of the multiresponse regression model, estimating the regression function becomes the main problem, as there is a correlation between the responses such that it is necessary to include a symmetric weight matrix into a penalized weighted least square (PWLS) optimization during the estimation process. This is, of course, very complicated mathematically. In this study, to estimate the regression function of the MNR model, we developed a PWLS optimization method for the MNR model proposed by a previous researcher, and used a reproducing kernel Hilbert space (RKHS) approach based on a smoothing spline to obtain the solution to the developed PWLS optimization. Additionally, we determined the symmetric weight matrix and optimal smoothing parameter, and investigated the consistency of the regression function estimator. We provide an illustration of the effects of the smoothing parameters for the estimation results using simulation data. In the future, the theory generated from this study can be developed within the scope of statistical inference, especially for the purpose of testing hypotheses involving multiresponse nonparametric regression models and multiresponse semiparametric regression models, and can be used to estimate the nonparametric component of a multiresponse semiparametric regression model used to model Indonesian toddlers’ standard growth charts.

In this paper, we propose modified spline estimators for nonparametric regression models with right-censored data, especially when the censored response observations are converted to synthetic data. Efficient implementation of these estimators depends on the set of knot points and an appropriate smoothing parameter. We use three algorithms, the default selection method (DSM), myopic algorithm (MA), and full search algorithm (FSA), to select the optimum set of knots in a penalized spline method based on a smoothing parameter, which is chosen based on different criteria, including the improved version of the Akaike information criterion (AICc), generalized cross validation (GCV), restricted maximum likelihood (REML), and Bayesian information criterion (BIC). We also consider the smoothing spline (SS), which uses all the data points as knots. The main goal of this study is to compare the performance of the algorithm and criteria combinations in the suggested penalized spline fits under censored data. A Monte Carlo simulation study is performed and a real data example is presented to illustrate the ideas in the paper. The results confirm that the FSA slightly outperforms the other methods, especially for high censoring levels.

In this work we introduce different modified estimators for the vector parameter and an unknown regression function g in semiparametric regression models when censored response observations are replaced with synthetic data points. The main idea is to study the effects of several covariates on a response variable censored on the right by a random censoring variable with an unknown probability distribution. To provide the estimation procedure for the estimators, we extend the conventional methodology to censored semiparametric regression using different smoothing methods such as smoothing spline (SS), kernel smoothing (KS), and regression spline (RS). In addition to estimating the parameters of the semiparametric model, we also provide a bootstrap technique to make inference on the parameters. A simulation study is carried out to show the performance and efficiency properties of the estimators and analyse the effects of the different censoring levels. Finally, the performance of the estimators is evaluated by a real right-censored data set.

This paper focuses on the adaptive spline (A-spline) fitting of the semiparametric regression model to time series data with right-censored observations. Typically, there are two main problems that need to be solved in such a case: dealing with censored data and obtaining a proper A-spline estimator for the components of the semiparametric model. The first problem is traditionally solved by the synthetic data approach based on the Kaplan–Meier estimator. In practice, although the synthetic data technique is one of the most widely used solutions for right-censored observations, the transformed data’s structure is distorted, especially for heavily censored datasets, due to the nature of the approach. In this paper, we introduced a modified semiparametric estimator based on the A-spline approach to overcome data irregularity with minimum information loss and to resolve the second problem described above. In addition, the semiparametric B-spline estimator was used as a benchmark method to gauge the success of the A-spline estimator. To this end, a detailed Monte Carlo simulation study and a real data sample were carried out to evaluate the performance of the proposed estimator and to make a practical comparison.

In this paper, we consider the estimation problem for the semiparametric regression model with censored data in which the number of explanatory variables p in the linear part is much larger than sample size n, often denoted as p $\gg$ n. The purpose of this paper is to study the effects of covariates on a response variable censored on the right by a random censoring variable with an unknown probability distribution. It should be noted that high variance and over-fitting are a major concern in such problems. Ordinary statistical methods for estimation cannot be applied directly to censored and high-dimensional data, and therefore a transformation is required. In the context of this paper, a synthetic data transformation is used for solving the censoring problem. We then apply the LASSO-type double-penalized least squares (DPLS) to achieve sparsity in the parametric component and use smoothing splines to estimate the nonparametric component. A Monte Carlo simulation study is performed to show the performance of the estimators and to analyse the effects of the different censoring levels. A real high-dimensional censored data example is used to illustrate the ideas discussed herein.

This paper considers a partially linear regression model relating a right-censored response variable to predictors and an extra covariate with measured error. The main problem here is that censorship and measurement error problems need to be solved to estimate the model correctly. In this sense, we propose three modified semiparametric estimators obtained from local polynomial regression, kernel smoothing, and B-spline smoothing methods based on kernel deconvolution approach and synthetic data transformation. Here, kernel deconvolution technique is used to solve the measurement error problem in the model and synthetic data transformation is considered to add the effect of censorship to the estimation procedure, which is a very common method in the literature. The performances of the introduced estimators are compared in the detailed Monte-Carlo simulation study. In addition, Carotid endarterectomy data is used as real-world data example and results are presented. According to the results, it is seen that the deconvoluted local polynomial method gives more qualified estimates than other two methods.