The mechanical properties of soft tissues play a key role in studying human injuries and their mitigation strategies. While such properties are indispensable for computational modelling of biological systems, they serve as important references in loading and failure experiments, and also for the development of tissue simulants. To date, experimental studies have measured the mechanical properties of peripheral tissues (e.g. skin) in-vivo and limited internal tissues ex-vivo in cadavers (e.g. brain and the heart). The lack of knowledge on a majority of human tissues inhibit their study for applications ranging from surgical planning, ballistic testing, implantable medical device development, and the assessment of traumatic injuries. The purpose of this work is to overcome such challenges through an extensive review of the literature reporting the mechanical properties of whole-body soft tissues from head to toe. Specifically, the available linear mechanical properties of all human tissues were compiled. Non-linear biomechanical models were also introduced, and the soft human tissues characterized using such models were summarized. The literature gaps identified from this work will help future biomechanical studies on soft human tissue characterization and the development of accurate medical models for the study and mitigation of injuries.

Storage of waste tyres causes serious environmental pollution and health issues, especially when they are left untreated in stockpiles and landfills. Waste tyres could be subjected to pyrolysis and activation in order to produce activated carbon, which is an effective adsorbent, and can find various applications, such as for wastewater treatment, removal of metals and dyes, energy storage devices, electrode materials, etc. Activated carbon (AC) is a non-polar and non-graphite material having high porosity and excellent adsorption capabilities, making it one of the most frequently used adsorbents in various industries. It is normally produced from carbon-rich materials such as coal, coconut shells, waste tyres, biowaste, etc. The use of waste tyres for the production of AC is a sustainable alternative to conventional sources (such as coconut shells and coal) as it supports the concept of a circular economy. Since AC sourced from waste tyres is a new area, this study reviews the methods for the preparation of AC, the types of activation, the forms of activated carbon, and the factors affecting the adsorption process. This study also reviews various applications of AC derived from waste tyres, with a specific focus on the removal of different pollutants from wastewater. Activated carbon derived from the waste tyres was found to be a versatile and economically viable carbon material, which can contribute towards safeguarding the environment and human health.

The development of foot ulcers is a common consequence of severe diabetes. Due to vascular disorders and impeded healing caused by the disease, most foot ulcers have been reported to be affected by body weight and progress with time. Also, abnormal distribution of plantar pressures has been observed to cause the formation of additional ulcers, which may collectively lead to traumatic amputations. While a study of such pathophysiology is not possible through experiments, a few computational modelling works have investigated diabetic foot ulcers. To date, ulcers with a few sizes and locations have been studied, and their effect on the plantar stresses has been quantified. In this work, we have attempted to study the effect of all possible ulcer locations on the generated plantar peak stresses and peak stress locations where additional ulcers may form. Also, the effect of ulcer location on the possible ulcer growth was investigated. A full-scale foot model was developed and a total of 52 ulcer locations were simulated separately, with standing and walking loads. The generated stresses were normalised with the foot size and statistically analysed to develop novel formulations for predicting peak plantar stresses and their locations for any known ulcer location. The results from this study are anticipated to provide important guidelines to doctors and medical practitioners for predicting foot ulcer progression in diabetic patients with existing ulcers and allow the administration of timely preventive interventions.